Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418848 | 1.00 | ESR2 (0.68) | ESR2ESR1 | |
| SCHEMBL2421292 | 0.93 | ESR2 (0.64) | ESR2ESR1 | |
| SCHEMBL2417559 | 0.93 | ESR2 (0.64) | ESR2ESR1 | |
| SCHEMBL12320150 | 0.91 | ESR2 (0.61) | ESR2ESR1 | |
| SCHEMBL2417470 | 0.91 | ESR2 (0.61) | ESR2ESR1 | |
| SCHEMBL12320882 | 0.90 | ESR2 (0.60) | ESR2ESR1 | |
| SCHEMBL2415427 | 0.90 | ESR2 (0.60) | ESR2ESR1 | |
| SCHEMBL2420997 | 0.90 | ESR2 (0.60) | ESR2ESR1 | |
| SCHEMBL2413798 | 0.89 | ESR2 (0.67) | ESR2ESR1 | |
| SCHEMBL12320126 | 0.89 | ESR2 (0.67) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1257264-A4 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO INC (US) | 2005-08-10 | — | — | EP | claimed |
| EP-1257264-A1 | ESTROGEN RECEPTOR MODULATORS | Merck & Co., Inc. (US) | 2002-11-20 | — | — | EP | claimed |
| WO-2001082923-A1 | ESTROGEN RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2001-11-08 | — | — | WO | claimed |