SCHEMBL6138092

SCHEMBL6138092

CC(O)C(NC(=O)Cc1ccccc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.58
PSMB8 P28062 1/20 0.57
PSMB5 P28074 1/20 0.57
MME P08473 1/20 0.57
CNR2 P34972 7/20 0.56
MEN1 O00255 2/20 0.55
KMT2A Q03164 2/20 0.55
CYP1A2 P05177 1/20 0.55
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 1/20 0.54
CNR1 P21554 1/20 0.53
HPGD P15428 2/20 0.52
MAPT P10636 1/20 0.51
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16114948 1.00 POLB (0.58) POLBPSMB8PSMB5MMECNR2
SCHEMBL6138095 1.00 POLB (0.58) POLBPSMB8PSMB5MMECNR2
SCHEMBL10417010 1.00 POLB (0.58) POLBPSMB8PSMB5MMECNR2
SCHEMBL4412847 0.88 POLB (0.59) POLBPSMB8PSMB5CNR2MEN1
SCHEMBL4412844 0.88 POLB (0.59) POLBPSMB8PSMB5CNR2MEN1
SCHEMBL10432164 0.88 POLB (0.59) POLBPSMB8PSMB5CNR2MEN1
SCHEMBL10840469 0.87 POLB (0.55) POLBPSMB8PSMB5CNR2MEN1
SCHEMBL27906833 0.87 POLB (0.55) POLBPSMB8PSMB5CNR2MEN1
SCHEMBL10840463 0.87 POLB (0.55) POLBPSMB8PSMB5CNR2MEN1
SCHEMBL16114864 0.84 POLB (0.59) POLBPSMB8PSMB5MMECNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240290431-A1 BIOMARKER AND DIAGNOSIS SYSTEM FOR COLORECTAL CANCER DETECTION HANGZHOU CALIBRA DIAGNOSTICS CO LTD (CN) 2024-08-29 US claimed
US-20230402131-A1 BIOMARKER AND DIAGNOSIS SYSTEM FOR COLORECTAL CANCER DETECTION HANGZHOU CALIBRA DIAGNOSTICS CO., LTD. (CN) 2023-12-14 US claimed
CN-115436633-A Biomarker for colorectal cancer detection and application thereof 杭州凯莱谱精准医疗检测技术有限公司 2022-12-06 CN claimed
CN-115440375-A Colorectal cancer prediction system and application thereof 杭州凯莱谱精准医疗检测技术有限公司 2022-12-06 CN claimed
CN-114755422-B Biomarker for colorectal cancer detection and application thereof 杭州凯莱谱精准医疗检测技术有限公司 2022-10-21 CN claimed
CN-114758719-B Colorectal cancer prediction system and application thereof 杭州凯莱谱精准医疗检测技术有限公司 2022-10-21 CN claimed
CN-114758719-A Colorectal cancer prediction system and application thereof 杭州凯莱谱精准医疗检测技术有限公司 2022-07-15 CN claimed
CN-114755422-A Biomarker for colorectal cancer detection and application thereof 杭州凯莱谱精准医疗检测技术有限公司 2022-07-15 CN claimed
CN-109182200-B Lysinibacillus fusiformis ZJB-17006 and application thereof 浙江工业大学 2020-10-09 CN claimed
CN-109321493-B B-lysine-resistant bacillus ZJB-17007 and application thereof 浙江工业大学 2020-10-02 CN claimed
CN-109321492-B Non-decarboxylation lechler bacterium ZJB-17008 and application thereof 浙江工业大学 2020-08-21 CN claimed
CN-109321490-B Enterobacter aerogenes ZJB-17003 and application thereof 浙江工业大学 2020-08-21 CN claimed
CN-109321497-B Lysine-elongated bacillus ZJB-17009 and application thereof 浙江工业大学 2020-07-28 CN claimed
CN-109321496-B Citrobacter freundii ZJB-17010 and application thereof 浙江工业大学 2020-06-23 CN claimed
CN-109321494-B Kluyveromyces intermedia ZJB-17004 and application thereof 浙江工业大学 2020-06-23 CN claimed
CN-109182201-B Enterobacter hesheng biological I type ZJB-17002 and application thereof 浙江工业大学 2020-06-23 CN claimed
EP-1047391-A4 ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS GILLETTE CO (US) 2005-01-19 EP claimed
US-6238655-B1 USEFUL IN THE FORMULATION OF DEODORANTS, ANTIPERSPIRANTS, BODY SPRAYS, AND OTHER SKIN TREATMENT COMPOSITIONS. THE GILLETTE COMPANY 2001-05-29 US claimed
EP-1047391-A1 ALPHA-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 2000-11-02 EP claimed
WO-1999030679-A1 α-AMIDES OF L-AMINO ACIDS AS FRAGRANCE PRECURSORS THE GILLETTE COMPANY (US) 1999-06-24 WO claimed