Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 16/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 14/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6137834 | 0.90 | MEN1 (0.41) | MAP2K1MAP2K2MEN1KMT2ATDP1 | |
| SCHEMBL6138038 | 0.86 | MEN1 (0.35) | MAP2K1MAP2K2MEN1KMT2ATDP1 | |
| SCHEMBL6138160 | 0.83 | IDO1 (0.38) | MAP2K1IDO1 | |
| SCHEMBL6137966 | 0.82 | MEN1 (0.35) | MEN1KMT2ATDP1IDO1 | |
| SCHEMBL6138143 | 0.77 | KMT2A (0.34) | MEN1KMT2ATDP1IDO1 | |
| SCHEMBL6138051 | 0.77 | IDO1 (0.34) | MEN1KMT2ATDP1IDO1 | |
| SCHEMBL6137953 | 0.74 | MAP2K1 (0.41) | MAP2K1MAP2K2MEN1KMT2ATDP1 | |
| SCHEMBL6138006 | 0.74 | MAP2K1 (0.41) | MAP2K1MAP2K2MEN1KMT2ATDP1 | |
| SCHEMBL6137941 | 0.72 | MAP2K1 (0.39) | MAP2K1MAP2K2MEN1KMT2ATDP1 | |
| SCHEMBL6137786 | 0.72 | NOTUM (0.43) | MAP2K1MAP2K2MEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144394-B1 | 1-HETEROCYCLE SUBSTITUTED DIARYLAMINES | WARNER LAMBERT CO (US) | 2005-08-24 | — | — | EP | claimed |