Sugi Predict

Sugi Predict / Compounds / SCHEMBL61386

SCHEMBL61386

SCHEMBL61386

O=C(O)c1cc2cc(O)ccc2[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMAD3 P84022 1/20 1.00
▸ FLT3 P36888 10/20 0.76
▸ PDGFRB P09619 2/20 0.76
▸ ABL1 P00519 1/20 0.76
▸ KIT P10721 1/20 0.76
▸ BCR P11274 1/20 0.76
▸ KDM4E B2RXH2 3/20 0.66
▸ HPGD P15428 3/20 0.66
▸ HSD17B10 Q99714 3/20 0.66
▸ ALDH1A1 P00352 2/20 0.66
▸ F7 P08709 1/20 0.66
▸ F3 P13726 1/20 0.66
▸ PIN1 Q13526 1/20 0.66
▸ PDPK1 O15530 1/20 0.66
▸ LMNA P02545 1/20 0.66
▸ TSHR P16473 1/20 0.66
▸ NFKB1 P19838 1/20 0.66
▸ APEX1 P27695 1/20 0.66
▸ CYP2C19 P33261 1/20 0.66
▸ TDP1 Q9NUW8 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2230377 0.86 FLT3 (1.00) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL3016664 0.85 SMAD3 (0.73) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL2732420 0.83 FLT3 (0.73) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL3282981 0.83 FLT3 (0.73) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL3640332 0.82 SMAD3 (0.69) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL27541945 0.82 SMAD3 (0.67) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL1842307 0.81 SMAD3 (0.68) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL29415437 0.81 SMAD3 (0.68) SMAD3FLT3PDGFRBABL1KIT
SCHEMBL1864105 0.80 FLT3 (0.69) SMAD3FLT3PDGFRBABL1KIT
5-Fluoroindole-2-Carboxylic Acid SCHEMBL209759 0.79 KDM4E (1.00) SMAD3FLT3KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 — — EP claimed
WO-2025085689-A1 EXTRACELLULAR SMALL MOLECULE ACTIVATORS TARGETING BESTROPHIN CHANNELS FOR DISEASE TREATMENT THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2025-04-24 — — WO claimed
CN-118994223-A Aluminum oxide nanotube crystalline material and preparation method and application thereof 中国科学院福建物质结构研究所 2024-11-22 — — CN claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 — — WO claimed
CN-110643032-B Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2022-01-28 — — CN claimed
CN-110643032-A Eight-arm polyethylene glycol, preparation method, functionalized derivative and modified biologically-relevant substance 厦门赛诺邦格生物科技股份有限公司 2020-01-03 — — CN claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 — — US claimed
CN-105866303-B A kind of detection method based on derivative measure various neurotransmitters in situ 曲阜师范大学 2018-05-25 — — CN claimed
EP-2948454-B1 TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETI (IN) 2017-05-31 — — EP claimed
CN-105866303-A Detecting method for determining various neurotransmitters on the basis of in situ derivation 曲阜师范大学 2016-08-17 — — CN claimed
WO-1992005761-A1 COSMETIC COMPOSITION COMPRISING A DISPERSION OF LIPIDIC VESICLES AS WELL AS MELANIC PIGMENTS L'OREAL (FR) 1992-04-16 — — WO claimed
EP-0467767-A1 Product based on flaky particles containing melanine pigment and process for their preparation L'OREAL (FR) 1992-01-22 — — EP claimed
EP-0446132-A1 Keratinous fibres dyeing process with 6 or 7-monohydroxyindols at acidic pH and compositions L'OREAL (FR) 1991-09-11 — — EP claimed
US-5034015-A Fade resistant hair dyes with better coloring ability L'OREAL (FR) 1991-07-23 — — US claimed
EP-0379409-A1 Products based on polymer particles containing melanine pigments, process for their preparation, and their use, particularly cosmetically L'OREAL (FR) 1990-07-25 — — EP claimed
EP-0376776-A2 Process for dyeing keratinous fibres with hydroxyindole associated with quinone and 1,4-benzoquinone L'OREAL (FR) 1990-07-04 — — EP claimed
EP-0360638-A1 Process for dyeing keratinous fibres with an indole derivative associated with a nitrite, and composition therefor L'OREAL (FR) 1990-03-28 — — EP claimed
EP-0271186-A1 Hydroxyindoles and their use in dyeing REPLIGEN CORPORATION (US) 1988-06-15 — — EP claimed
US-4042329-A Method and device for detecting cholesterol BECTON, DICKINSON AND COMPANY (US) 1977-08-16 — — US claimed
US-3964871-A GLUCOSE OXIDASE, HORSERADISH PEROXIDASE BECTON, DICKINSON AND COMPANY (US) 1976-06-22 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS SMAD3 4122/4885FLT3 1197/4885PDGFRB 1655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.