SCHEMBL6138615

SCHEMBL6138615

Cc1csc(NC(=O)c2nc(Sc3nccn3C)ccc2Sc2ccc(F)cc2)n1.Cc1csc(NC(=O)c2nc(Sc3nnc[nH]3)ccc2Sc2ccc(F)cc2)n1

nearest known ligand 0.68

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GCK P35557 18/20 0.68
GRM5 P41594 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2211407 0.91 GCK (0.75) GCKGRM5
SCHEMBL2212232 0.90 GCK (0.68) GCKGRM5
SCHEMBL2208954 0.81 GCK (0.59) GCKGRM5
SCHEMBL2213370 0.81 GCK (0.73) GCK
SCHEMBL2210529 0.81 GCK (1.00) GCKGRM5
SCHEMBL2210335 0.79 GCK (0.54) GCK
SCHEMBL2252571 0.79 GCK (0.75) GCKGRM5
SCHEMBL2214206 0.78 GCK (0.75) GCKGRM5
SCHEMBL2663135 0.78 GCK (0.48) GCKGRM5
SCHEMBL2643097 0.78 GCK (0.52) GCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1598349-A1 NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES BANYU PHARMACEUTICAL CO., LTD. (JP) 2005-11-23 EP claimed