SCHEMBL6138842

SCHEMBL6138842

CC(=C(O)O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.52
CES2 O00748 3/20 0.48
CES1 P23141 3/20 0.48
PTGS2 P35354 2/20 0.43
TSHR P16473 3/20 0.43
ALDH1A1 P00352 2/20 0.43
DAO P14920 1/20 0.43
NAPRT Q6XQN6 1/20 0.43
MAPT P10636 2/20 0.40
CYP19A1 P11511 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
LMNA P02545 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
F12 P00748 1/20 0.39
F7 P08709 1/20 0.39
F3 P13726 1/20 0.39
PKM P14618 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1035354 0.87 ESR1 (0.56) ESR1CES2CES1PTGS2TSHR
SCHEMBL3902058 0.87 ESR1 (0.56) ESR1CES2CES1PTGS2TSHR
SCHEMBL11844374 0.87 ESR1 (0.56) ESR1CES2CES1PTGS2TSHR
SCHEMBL23278527 0.84 ESR1 (0.61) ESR1CES2CES1PTGS2TSHR
SCHEMBL8676275 0.81 ESR1 (0.58) ESR1CES2CES1PTGS2TSHR
SCHEMBL58000 0.81 ESR1 (0.52) ESR1CES2CES1PTGS2TSHR
SCHEMBL9806361 0.79 ESR1 (0.77) ESR1CES2CES1PTGS2CYP19A1
SCHEMBL3797764 0.79 ESR1 (0.50) ESR1CES2CES1PTGS2TSHR
SCHEMBL3797762 0.79 ESR1 (0.50) ESR1CES2CES1PTGS2TSHR
SCHEMBL16933865 0.77 ESR1 (0.48) ESR1CES2CES1PTGS2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1099691-B1 N-Sulfonyloxyimide compound and radiation-sensitive resin composition using the same JSR CORP (JP) 2005-03-02 EP claimed
EP-0819981-B1 Radiation sensitive resin composition JSR CORP (JP) 2002-06-05 EP claimed
EP-0435418-B1 A dispersant/antioxidant viscosity index improving lubricant additive TEXACO DEVELOPMENT CORP (US) 1995-01-04 EP claimed