Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 7/20 | 0.77 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.77 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.77 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.73 |
| ▸ | USP2 | O75604 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 4/20 | 0.59 |
| ▸ | CA2 | P00918 | 4/20 | 0.59 |
| ▸ | CASP7 | P55210 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.58 |
| ▸ | MDM4 | O15151 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14983114 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A | |
| SCHEMBL16509991 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A | |
| SCHEMBL14125341 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A | |
| SCHEMBL12382033 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A | |
| SCHEMBL14983107 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A | |
| SCHEMBL12244776 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A | |
| SCHEMBL13760061 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A | |
| SCHEMBL13908432 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A | |
| SCHEMBL18993218 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A | |
| SCHEMBL13587976 | 1.00 | GPBAR1 (0.77) | GPBAR1SLC10A2NR1H4TBXA2RPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150685-A4 | PHOSPHOCHOLINE SURFACTANTS AND THEIR USE | SUPERGEN INC (US) | 2005-06-15 | — | — | EP | disclosed |
| US-6489369-B1 | INSOLUBLE OR SPARINGLY WATER SOLUBLE DRUGS SUCH AS ETOPOSIDE, PACLITAXEL, PROPOFOL OR CYCLOSPORINS, BIODEGRADABLE/ -COMPATIBLE STEROL SOLUBILIZERS, CARRIERS AND DILUENTS HAVING STORAGE STABILITY | SUPERGEN, INC. | 2002-12-03 | — | — | US | disclosed |
| EP-1150685-A1 | PHOSPHOCHOLINE SURFACTANTS AND THEIR USE | SuperGen, Inc. (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000045822-A1 | PHOSPHOCHOLINE SURFACTANTS AND THEIR USE | SUPERGEN, INC. (US) | 2000-08-10 | — | — | WO | disclosed |