Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 4/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6138863 | 1.00 | HRH3 (0.49) | HRH3HRH4MCHR1CHRM1HTR2A | |
| Hydrochloric Acid SCHEMBL6139049 | 0.99 | HRH3 (0.48) | HRH3HRH4MCHR1CHRM1HTR2A | |
| Hydrochloric Acid SCHEMBL6139057 | 0.99 | HRH3 (0.48) | HRH3HRH4MCHR1CHRM1HTR2A | |
| SCHEMBL6138545 | 0.89 | HRH3 (0.51) | HRH3HDAC1HDAC8HDAC6HDAC2 | |
| SCHEMBL6138501 | 0.89 | HRH3 (0.51) | HRH3HDAC1HDAC8HDAC6HDAC2 | |
| Hydrochloric Acid SCHEMBL6138839 | 0.88 | HRH3 (0.50) | HRH3HDAC1HDAC8HDAC6HDAC2 | |
| Hydrochloric Acid SCHEMBL6138827 | 0.88 | HRH3 (0.50) | HRH3HDAC1HDAC8HDAC6HDAC2 | |
| SCHEMBL6138909 | 0.80 | HDAC1 (0.54) | HDAC1HDAC8HDAC6HDAC2HDAC3 | |
| SCHEMBL6138916 | 0.80 | HDAC1 (0.54) | HDAC1HDAC8HDAC6HDAC2HDAC3 | |
| Hydrochloric Acid SCHEMBL6813385 | 0.80 | HRH3 (0.47) | HRH3HRH4MCHR1CHRM1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1215203-B1 | HYDROXAMIC ACID DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2005-02-16 | — | — | EP | claimed |
| US-6770644-B1 | Hydroxamic acid derivatives, process for the production thereof and drug containing the same as the active ingredient | ONO PHARMACEUTICALS CO., LTD. (JP) | 2004-08-03 | — | — | US | claimed |
| EP-1215203-A1 | HYDROXAMIC ACID DERIVATIVES, PROCESS FOR THE PRODUCTION THEREOF AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-06-19 | — | — | EP | claimed |