Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLM | Q9NP87 | 2/20 | 0.44 |
| ▸ | POLK | Q9UBT6 | 2/20 | 0.44 |
| ▸ | POLL | Q9UGP5 | 2/20 | 0.44 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11420384 | 0.89 | POLM (0.48) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL11419979 | 0.87 | KMT2A (0.46) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL16756216 | 0.86 | MEN1 (0.50) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL16756225 | 0.86 | MEN1 (0.50) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL16756207 | 0.86 | MEN1 (0.50) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL16756224 | 0.86 | MEN1 (0.50) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL9179143 | 0.85 | POLM (0.59) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL28309018 | 0.85 | POLM (0.59) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL11577818 | 0.85 | POLM (0.59) | POLMPOLKPOLLPOLHMEN1 | |
| SCHEMBL16756197 | 0.84 | MEN1 (0.51) | POLMPOLKPOLLPOLHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1259470-A4 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2005-06-15 | — | — | EP | disclosed |
| EP-1259470-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | Yang, Zhenhua (US) | 2002-11-27 | — | — | EP | disclosed |
| WO-2001059067-A2 | A GROUP OF ANTI-CANCER COMPOUNDS WITH SPECIFIC STRUCTURE AND THEIR PRODUCTION METHOD | YANG ZHENHUA (US) | 2001-08-16 | — | — | WO | disclosed |