Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1B | P47901 | 20/20 | 0.79 |
| ▸ | OXTR | P30559 | 11/20 | 0.79 |
| ▸ | AVPR1A | P37288 | 11/20 | 0.79 |
| ▸ | AVPR2 | P30518 | 3/20 | 0.69 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4590483 | 1.00 | AVPR1B (0.79) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL6140538 | 0.94 | AVPR1B (0.82) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL4590067 | 0.94 | AVPR1B (0.82) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL4590080 | 0.93 | AVPR1B (0.79) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL6140940 | 0.93 | AVPR1B (0.79) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL6139834 | 0.91 | AVPR1B (0.86) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL4590182 | 0.91 | AVPR1B (0.86) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL4590365 | 0.91 | AVPR1B (0.80) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL6140323 | 0.91 | AVPR1B (0.80) | AVPR1BOXTRAVPR1AAVPR2GPR65 | |
| SCHEMBL6140418 | 0.90 | AVPR1B (0.75) | AVPR1BOXTRAVPR1AAVPR2GPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6864277-B2 | 1,3-dihydro-2H-indol-2-one derivatives, method for preparing same and pharmaceutical compositions containing them | SANOFI-SYNTHELABO (FR) | 2005-03-08 | — | — | US | claimed |
| US-6864277-B2 | 1,3-dihydro-2H-indol-2-one derivatives, method for preparing same and pharmaceutical compositions containing them | SANOFI-SYNTHELABO (FR) | 2005-03-08 | — | — | US | disclosed |