SCHEMBL6140486

SCHEMBL6140486

CSc1ccc(OCc2ccccc2)c(C2=C(c3cccc(C(=O)OCc4ccccc4)c3)CCC2)c1

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER1 P34995 20/20 0.84
CYP2C9 P11712 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14499132 0.92 PTGER1 (1.00) PTGER1CYP2C9
SCHEMBL5619333 0.86 PTGER1 (0.82) PTGER1CYP2C9
SCHEMBL5620444 0.84 PTGER1 (0.84) PTGER1CYP2C9
SCHEMBL5621051 0.82 PTGER1 (0.77) PTGER1CYP2C9
SCHEMBL5619606 0.81 PTGER1 (0.79) PTGER1CYP2C9
SCHEMBL5620526 0.81 PTGER1 (0.60) PTGER1CYP2C9
SCHEMBL5621974 0.79 PTGER1 (0.82) PTGER1CYP2C9
SCHEMBL8676505 0.79 PTGER1 (0.77) PTGER1CYP2C9
SCHEMBL5619861 0.77 PTGER1 (0.84) PTGER1CYP2C9
SCHEMBL5619894 0.77 PTGER1 (1.00) PTGER1CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7232821-B2 (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives GLAXO GROUP LIMITED (GB) 2007-06-19 US disclosed
US-7232821-B2 (2-((2-alkoxy)-phenyl) -cyclopent-1enyl) aromatic carbo and heterocyclic acid and derivatives GLAXO GROUP LIMITED (GB) 2007-06-19 US disclosed
EP-1492757-A1 (2-((2-ALKOXY)-PHENYL)-CYCLOPENT-1-ENYL) AROMATIC CARBO- AND HETEROCYCLIC CARBOXYLIC ACID AND DERIVATIVES GLAXO GROUP LIMITED (GB) 2005-01-05 EP disclosed
WO-2003084917-A1 (2-((2-ALKOXY) -PHENYL) -CYCLOPENT-1-ENYL) AROMATIC CARBO AND HETEROCYCLIC ACID AND DERIVATIVES GLAXO GROUP LIMITED (GB) 2003-10-16 WO disclosed