Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.48 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.46 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PAK4 | O96013 | 1/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | RET | P07949 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6109554 | 0.85 | MCHR1 (0.60) | MCHR1ALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL3414717 | 0.83 | MCHR1 (0.65) | MCHR1ALDH1A1TMEM97SIGMAR1 | |
| SCHEMBL3762391 | 0.82 | MCHR1 (0.53) | MCHR1ALDH1A1HPGDPOLBTMEM97 | |
| SCHEMBL3760668 | 0.82 | MCHR1 (0.47) | MCHR1ALDH1A1HPGDPOLBMAPK1 | |
| SCHEMBL1559086 | 0.80 | HPGD (0.53) | MCHR1ALDH1A1KDM4EHPGDTLR9 | |
| SCHEMBL3004623 | 0.79 | HPGD (0.68) | ALDH1A1KDM4EHPGDPOLBHTT | |
| SCHEMBL12505361 | 0.79 | POLB (0.56) | POLBHTTSMN1; SMN2 | |
| SCHEMBL13886657 | 0.78 | MCHR1 (0.78) | MCHR1ALDH1A1KDM4EHPGDAPP | |
| SCHEMBL14094304 | 0.78 | TLR9 (0.54) | MCHR1ALDH1A1KDM4EHPGDTLR9 | |
| SCHEMBL6110566 | 0.77 | MCHR1 (1.00) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1497260-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM Pharma A/S (DK) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003087045-A1 | NOVEL METHOXYBENZAMIDE COMPOUNDS FOR USE IN MCH RECEPTOR RELATED DISORDERS | 7TM PHARMA A/S (DK) | 2003-10-23 | — | — | WO | disclosed |