Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.53 |
| ▸ | ACHE | P22303 | 5/20 | 0.53 |
| ▸ | MAOB | P27338 | 5/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4853600 | 0.90 | BCHE (0.51) | BCHEACHEMAOBESR1SMN1; SMN2 | |
| SCHEMBL4849936 | 0.90 | BCHE (0.51) | BCHEACHEMAOBESR1SMN1; SMN2 | |
| SCHEMBL4853639 | 0.87 | ABCG2 (0.51) | BCHEACHEMAOBESR1SMN1; SMN2 | |
| SCHEMBL4851382 | 0.87 | ABCG2 (0.51) | BCHEACHEMAOBESR1SMN1; SMN2 | |
| SCHEMBL4853019 | 0.79 | MAPT (0.61) | BCHEACHEMAOBSMN1; SMN2MEN1 | |
| SCHEMBL4854277 | 0.79 | MAPT (0.61) | BCHEACHEMAOBSMN1; SMN2MEN1 | |
| SCHEMBL7193109 | 0.79 | MAPT (0.67) | MAOBSMN1; SMN2MEN1KMT2AABCG2 | |
| SCHEMBL8154777 | 0.79 | MAPT (0.67) | MAOBSMN1; SMN2MEN1KMT2AABCG2 | |
| SCHEMBL7193105 | 0.79 | MAPT (0.67) | MAOBSMN1; SMN2MEN1KMT2AABCG2 | |
| SCHEMBL4857305 | 0.77 | ABCG2 (0.59) | BCHEACHEMAOBSMN1; SMN2ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515940-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | Lica Pharmaceuticals A/S (DK) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003097574-A2 | AMINOALKOXY-FUNCTIONAL CHALCONES | LICA PHARMACEUTICALS A/S (DK) | 2003-11-27 | — | — | WO | disclosed |