Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | HPGD | P15428 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27374650 | 0.85 | MEN1 (0.84) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL4014301 | 0.82 | MEN1 (0.67) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL4014336 | 0.82 | MEN1 (0.61) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL12218388 | 0.82 | MAPT (0.72) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL14209682 | 0.81 | MAPT (0.62) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL10016463 | 0.81 | MEN1 (1.00) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL4293548 | 0.80 | MEN1 (0.74) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL742018 | 0.79 | MEN1 (0.77) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL4296024 | 0.79 | MEN1 (0.65) | MEN1KMT2AMAPTHPGDL3MBTL1 | |
| SCHEMBL27374742 | 0.79 | MEN1 (0.65) | MEN1KMT2AMAPTHPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558567-A1 | NOVEL AMIDE COMPOUNDS WITH MCH ANTAGONISTIC EFFECT AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2005-08-03 | — | — | EP | disclosed |
| WO-2004039764-A1 | NOVEL AMIDE COMPOUNDS WITH MCH ANTAGONISTIC EFFECT AND MEDICAMENTS COMPRISING SAID COMPOUNDS | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2004-05-13 | — | — | WO | disclosed |