SCHEMBL6142018

SCHEMBL6142018

O=C(O)CC(CC(O)C(=O)O)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.59
FOLH1 Q04609 2/20 0.50
SLC22A6 Q4U2R8 1/20 0.43
TET2 Q6N021 6/20 0.42
KDM4A O75164 2/20 0.42
KDM4C Q9H3R0 2/20 0.42
KDM2A Q9Y2K7 2/20 0.42
TET3 O43151 2/20 0.42
CPA1 P15085 2/20 0.42
CPB1 P15086 1/20 0.42
CPA3 P15088 1/20 0.42
CPB2 Q96IY4 1/20 0.42
OR51E2 Q9H255 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
TET1 Q8NFU7 1/20 0.39
GABRR1 P24046 2/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL524140 0.87 FOLH1 (0.62) SMN1; SMN2FOLH1SLC22A6CPA1CPB1
SCHEMBL14591440 0.87 FOLH1 (0.62) SMN1; SMN2FOLH1SLC22A6CPA1CPB1
Hydrochloric Acid SCHEMBL8841246 0.84 FOLH1 (0.59) SMN1; SMN2FOLH1SLC22A6CPA1CPB1
SCHEMBL270456 0.84 FOLH1 (0.67) SMN1; SMN2FOLH1SLC22A6CPA1CPB1
SCHEMBL27199098 0.82 SLC22A6 (0.52) SMN1; SMN2FOLH1SLC22A6CPA1CPB1
SCHEMBL7617173 0.80 SLC22A6 (0.57) SMN1; SMN2FOLH1SLC22A6CPA1CPB1
SCHEMBL1451353 0.79 FOLH1 (0.54) SMN1; SMN2FOLH1SLC22A6CPA1CPB1
SCHEMBL17372970 0.78 FOLH1 (0.60) SMN1; SMN2FOLH1SLC22A6TET2KDM4A
Tricarballylic Acid SCHEMBL1821947 0.78 FOLH1 (0.65) SMN1; SMN2FOLH1SLC22A6CPA1CPB1
Tricarballylic Acid SCHEMBL34866 0.78 FOLH1 (0.65) SMN1; SMN2FOLH1SLC22A6CPA1CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3003411-A1 DEGRADABLE HAEMOSTAT COMPOSITION Medtrade Products Limited (GB) 2016-04-13 EP claimed
WO-2014191738-A1 DEGRADABLE HAEMOSTAT COMPOSITION MEDTRADE PRODUCTS LIMITED (GB) 2014-12-04 WO claimed
WO-2025263641-A1 COMPOSITION COMPRISING GLYCOLIPID, CATIONIC POLYMER AND (POLY)HYDROXY ACID L'OREAL (FR) 2025-12-26 WO disclosed
WO-2022118982-A1 PROCESS FOR TREATING KERATIN FIBERS L'OREAL (FR) 2022-06-09 WO disclosed
EP-1492486-A2 UREA COMPOSITIONS Yu, Ruey J., Dr. (US) 2005-01-05 EP disclosed
WO-2003086291-A2 UREA COMPOSITIONS YU RUEY J (US) 2003-10-23 WO disclosed