Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.33 |
| ▸ | LSS | P48449 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142321 | 0.96 | HTR2C (0.43) | HTR2CP2RY14ESR2DGAT1IDO1 | |
| SCHEMBL6142185 | 0.95 | HTR2C (0.42) | HTR2CP2RY14ESR2DGAT1IDO1 | |
| SCHEMBL6141795 | 0.93 | P2RY14 (0.46) | HTR2CP2RY14ESR2DGAT1IDO1 | |
| SCHEMBL6142069 | 0.85 | GRIA1 (0.36) | ESR2ALDH1A1LMNAMAPTHSD11B1 | |
| SCHEMBL6141684 | 0.85 | FFAR1 (0.37) | ESR2ALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL7859049 | 0.85 | ESR2 (0.35) | ESR2ALDH1A1LMNAMAPTCYP2C9 | |
| SCHEMBL6142186 | 0.85 | ESR2 (0.35) | ESR2IDO1LSSALDH1A1LMNA | |
| SCHEMBL6142243 | 0.85 | ACACB (0.33) | ESR2MAOBGRM2 | |
| SCHEMBL6142060 | 0.82 | HTR2C (0.42) | HTR2CP2RY14IDO1CNR1HSD11B1 | |
| SCHEMBL6141733 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930286-B1 | LIQUID-CRYSTAL ALKENYLTOLAN DERIVATIVE, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORP (JP) | 2005-01-12 | — | — | EP | disclosed |
| US-6333080-B1 | HIGH ANISOTROPY, HIGH ELASTIC CONSTANT RATIO, EXCELLENT COMPARABILITY WITH OTHER LIQUID-CRYSTAL COMPOUNDS, AND LOW VISCOSITY AND ARE CHEMICALLY AND PHYSICALLY STABLE | CHISSO CORPORATION (JP) | 2001-12-25 | — | — | US | disclosed |
| EP-0930286-A1 | LIQUID-CRYSTAL ALKENYLTOLAN DERIVATIVE, LIQUID-CRYSTAL COMPOSITION, AND LIQUID-CRYSTAL DISPLAY ELEMENT | CHISSO CORPORATION (JP) | 1999-07-21 | — | — | EP | disclosed |