Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.57 |
| ▸ | CTSD | P07339 | 3/20 | 0.57 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3913420 | 1.00 | BACE1 (0.57) | BACE1CTSDBACE2 | |
| SCHEMBL3913425 | 1.00 | BACE1 (0.57) | BACE1CTSDBACE2 | |
| SCHEMBL6149749 | 1.00 | BACE1 (0.57) | BACE1CTSDBACE2 | |
| SCHEMBL3904850 | 0.94 | BACE1 (0.58) | BACE1CTSDBACE2 | |
| SCHEMBL3904843 | 0.94 | BACE1 (0.58) | BACE1CTSDBACE2 | |
| SCHEMBL6144309 | 0.94 | BACE1 (0.58) | BACE1CTSDBACE2 | |
| SCHEMBL3914188 | 0.84 | BACE1 (0.59) | BACE1CTSDBACE2 | |
| SCHEMBL3901850 | 0.83 | BACE1 (0.55) | BACE1CTSDBACE2 | |
| SCHEMBL3901844 | 0.83 | BACE1 (0.55) | BACE1CTSDBACE2 | |
| SCHEMBL5351658 | 0.81 | BACE1 (0.76) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1503980-A2 | SUBSTITUTED HYDROXYETHYLAMINES | Elan Pharmaceuticals, Inc. (US) | 2005-02-09 | — | — | EP | disclosed |
| WO-2003072535-A2 | SUBSTITUTED HYDROXYETHYLAMINES | ELAN PHARMACEUTICALS, INC. (US) | 2003-09-04 | — | — | WO | disclosed |