SCHEMBL6150787

SCHEMBL6150787

CO/N=C(/C(=O)O)c1ccccc1COc1cc(Cl)c(OCC=C(F)C(F)(F)F)c(Cl)c1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 8/20 0.45
MRGPRX4 Q96LA9 4/20 0.34
TP53 P04637 1/20 0.34
HTT P42858 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
PDCD1 Q15116 1/20 0.33
CD274 Q9NZQ7 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6150788 1.00 HIF1A (0.45) HIF1AMRGPRX4TP53HTTMAOA
SCHEMBL5080503 0.92 HIF1A (0.37) HIF1AMRGPRX4TP53HTTMAOA
SCHEMBL5080502 0.92 HIF1A (0.55) HIF1AMRGPRX4MAOAMAOBPDCD1
SCHEMBL5077135 0.91 HIF1A (0.47) HIF1AMRGPRX4TP53HTTMEN1
SCHEMBL5077133 0.91 HIF1A (0.47) HIF1AMRGPRX4TP53HTTMEN1
SCHEMBL5077131 0.91 HIF1A (0.47) HIF1AMRGPRX4TP53HTTMEN1
SCHEMBL6150643 0.91 HIF1A (0.48) HIF1AMRGPRX4TP53HTTMAOA
SCHEMBL6150645 0.91 HIF1A (0.48) HIF1AMRGPRX4TP53HTTMAOA
SCHEMBL5079443 0.91 HIF1A (0.45) HIF1AMRGPRX4MAOAMAOBPDCD1
SCHEMBL5079434 0.91 HIF1A (0.45) HIF1AMRGPRX4MAOAMAOBPDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1494991-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES Isagro Ricerca S.r.l. (IT) 2005-01-12 EP disclosed
WO-2003087032-A1 ANALOGOUS COMPOUNDS OF STROBILURINES AND THEIR USE AS ACARICIDES AND INSECTICIDES ISAGRO RICERCA S.R.L. (IT) 2003-10-23 WO disclosed