Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.54 |
| ▸ | PPARG | P37231 | 16/20 | 0.54 |
| ▸ | PPARD | Q03181 | 9/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6150158 | 0.85 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL5364844 | 0.84 | PPARA (0.52) | PPARAPPARGPPARD | |
| SCHEMBL6682035 | 0.83 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5364268 | 0.83 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL14501925 | 0.83 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5364266 | 0.83 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL5362635 | 0.83 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL6659254 | 0.81 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3968108 | 0.79 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6150506 | 0.78 | PPARA (0.57) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | claimed |
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |