Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151751 | 0.88 | EDNRB (0.69) | EDNRAEDNRB | |
| SCHEMBL6152492 | 0.88 | EDNRA (0.80) | EDNRAEDNRB | |
| SCHEMBL6151520 | 0.86 | EDNRB (1.00) | EDNRAEDNRB | |
| SCHEMBL6151616 | 0.85 | EDNRB (0.75) | EDNRAEDNRB | |
| SCHEMBL6151196 | 0.85 | EDNRA (0.75) | EDNRAEDNRB | |
| SCHEMBL27466198 | 0.84 | EDNRB (0.81) | EDNRAEDNRB | |
| SCHEMBL27456257 | 0.84 | EDNRB (0.73) | EDNRAEDNRB | |
| SCHEMBL6151493 | 0.82 | EDNRB (0.77) | EDNRAEDNRB | |
| SCHEMBL6150782 | 0.81 | EDNRB (0.66) | EDNRAEDNRB | |
| SCHEMBL7228721 | 0.81 | EDNRA (1.00) | EDNRAEDNRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1498419-A1 | Process for preparing alkali metal salts of hydrophobic sulfonamides | ENCYSIVE PHARMACEUTICALS INC. (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1498418-A1 | Sulfonamides for treatment of endothelin-mediated disorders | ENCYSIVE PHARMACEUTICALS INC. (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1048657-A1 | Thienyl-, furyl-, pyrrolyl- and biphenylsulfonamides and derivatives thereof that modulate the activity of endothelin | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2000-11-02 | — | — | EP | disclosed |