Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 20/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.67 |
| ▸ | HTR2A | P28223 | 3/20 | 0.64 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151395 | 0.84 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL6152119 | 0.83 | SLC6A4 (0.72) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL6945836 | 0.83 | SLC6A4 (0.63) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL6152091 | 0.83 | SLC6A4 (0.64) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL6152250 | 0.83 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL6151217 | 0.82 | SLC6A4 (0.59) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL7062688 | 0.81 | SLC6A4 (0.64) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL6946108 | 0.81 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL6152684 | 0.80 | SLC6A4 (0.68) | SLC6A4SLC6A2SLC6A3HTR2AKCNH2 | |
| SCHEMBL6152056 | 0.80 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268396-B1 | DIPHENYL ETHER COMPOUNDS USEFUL IN THERAPY | PFIZER LTD (GB) | 2005-07-20 | — | — | EP | disclosed |