Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2964698 | 1.00 | KCNH2 (0.64) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2966219 | 0.91 | KCNH2 (0.70) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2966221 | 0.91 | KCNH2 (0.70) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6095179 | 0.89 | MEN1 (0.56) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2956759 | 0.88 | KCNH2 (0.62) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2969679 | 0.86 | KCNH2 (0.63) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2959969 | 0.86 | KCNH2 (0.61) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6316718 | 0.86 | MEN1 (0.53) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6316723 | 0.86 | MEN1 (0.53) | KCNH2KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6619543 | 0.86 | MEN1 (0.53) | KCNH2KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235831-B1 | NEW OXABISPIDINE COMPOUNDS USEFUL IN THE TREATMENT OF CARDIAC ARRHYTHMIAS | ASTRAZENECA AB (SE) | 2005-03-30 | — | — | EP | claimed |