Hypochlorous Acid

Hypochlorous Acid

SCHEMBL6151500

Nc1ccccc1N.OCl.OCl

nearest known ligand 0.77

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.77
ALOX15 P16050 2/20 0.77
CASP1 P29466 1/20 0.77
CASP7 P55210 1/20 0.77
SMN1; SMN2 Q16637 1/20 0.77
TSHR P16473 6/20 0.56
ALDH1A1 P00352 6/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
GAA P10253 4/20 0.45
TDP1 Q9NUW8 3/20 0.45
MAPT P10636 2/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
APOBEC3G Q9HC16 1/20 0.45
NPC1 O15118 1/20 0.45
RAB9A P51151 1/20 0.45
HSD17B10 Q99714 3/20 0.44
HPGD P15428 2/20 0.44
KEAP1 Q14145 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL5481727 0.88 CYP3A4 (0.83) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Hydrogen Peroxide SCHEMBL296759 0.88 CYP3A4 (0.83) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL29351116 0.88
SCHEMBL5167521 0.88 CYP3A4 (1.00) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL6187 0.88
Hydrogen Peroxide SCHEMBL3214813 0.85 CYP3A4 (0.77) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL6537125 0.85 CYP3A4 (0.77) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Hydrogen Peroxide SCHEMBL28372013 0.85 CYP3A4 (0.77) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
Methyl Alcohol SCHEMBL9725170 0.85 CYP3A4 (0.77) CYP3A4ALOX15CASP1CASP7SMN1; SMN2
SCHEMBL28298522 0.85 CYP3A4 (0.77) CYP3A4ALOX15CASP1CASP7SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050095591-A1 Using myoglobin, myosin light chain, myosin heavy chain and total creatine kinase expression as a stratifying tool for predicting vascular events PROTEINLOGIC LIMITED (AU) 2005-05-05 US disclosed
EP-1385879-A4 REPRODUCTIVE CANCER DIAGNOSIS AND THERAPY UNIV QUEENSLAND (AU) 2005-02-02 EP disclosed
US-20040157227-A1 Reproductive cancer diagnosis and therapy QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2004-08-12 US disclosed
EP-1436615-A1 DIAGNOSTIC ASSAY University of Sydney (AU) 2004-07-14 EP disclosed
EP-1385879-A1 REPRODUCTIVE CANCER DIAGNOSIS AND THERAPY QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2004-02-04 EP disclosed
WO-2002090387-A1 REPRODUCTIVE CANCER DIAGNOSIS AND THERAPY QUEENSLAND UNIVERSITY OF TECHNOLOGY (AU) 2002-11-14 WO disclosed
WO-2002023191-A1 DIAGNOSTIC ASSAY UNIVERSITY OF SYDNEY (AU) 2002-03-21 WO disclosed