Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.67 |
| ▸ | RAD52 | P43351 | 2/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 5/20 | 0.38 |
| ▸ | DRD2 | P14416 | 8/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | S100B | P04271 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6419791 | 0.99 | GAA (0.65) | GAARAD52MAPTKDM4EMAPK1 | |
| SCHEMBL5707918 | 0.95 | GAA (0.60) | GAARAD52MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL5707959 | 0.94 | GAA (0.59) | GAARAD52MAPTKDM4EMAPK1 | |
| SCHEMBL5707912 | 0.92 | GAA (0.63) | GAARAD52MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL5707935 | 0.91 | GAA (0.62) | GAARAD52MAPTKDM4EMAPK1 | |
| SCHEMBL5707908 | 0.87 | GAA (0.58) | GAARAD52MAPTKDM4EMAPK1 | |
| Hydrochloric Acid SCHEMBL5707937 | 0.86 | GAA (0.56) | GAARAD52MAPTKDM4EMAPK1 | |
| SCHEMBL6151541 | 0.84 | GAA (0.72) | GAARAD52MAPTKDM4EMAPK1 | |
| SCHEMBL6152983 | 0.82 | GAA (0.70) | GAARAD52MAPTKDM4EMAPK1 | |
| SCHEMBL22652063 | 0.82 | GAA (0.70) | GAARAD52MAPTKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1518860-A1 | Triazacyclononane derivatives substituted on at least one of the nitrogene atoms by a 4-aminophenyle group for dyeing keratinic fibres | L'OREAL (FR) | 2005-03-30 | — | — | EP | claimed |