SCHEMBL6151577

SCHEMBL6151577

Fc1c(F)c(Br)c(Br)c(Br)c1Br

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
MAPK1 P28482 1/20 0.33
RECQL P46063 1/20 0.33
HIF1A Q16665 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4600187 0.95 CA1 (0.31) CA1CA2CA4CA6ALDH1A1
SCHEMBL29665756 0.90
SCHEMBL2166552 0.90
SCHEMBL6150916 0.90 CA1 (0.33) CA1CA2CA4CA6ALDH1A1
SCHEMBL164556 0.84
SCHEMBL350227 0.80
SCHEMBL7194514 0.79
Bromide SCHEMBL6296242 0.76
SCHEMBL2937287 0.76
SCHEMBL3286814 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114349777-B Condensed ring compound containing two boron atoms and four oxygen atoms and organic electroluminescent device 中国科学院长春应用化学研究所 2024-02-13 CN disclosed
CN-114349777-A Fused ring compound containing two boron atoms and four oxygen group atoms and organic electroluminescent device 中国科学院长春应用化学研究所 2022-04-15 CN disclosed
EP-0944564-B9 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORP (US) 2005-01-19 EP disclosed
US-20030163000-A1 Halogen exchange reactions and catalysts therefor CHORDIP LTD. (GB) 2003-08-28 US disclosed
EP-1054853-B1 CATALYST RECOVERY FOR HALOGEN EXCHANGE REACTIONS ALBEMARLE CORP (US) 2003-03-19 EP disclosed
EP-1288196-A1 Process for the preparation of organo guanidinium salts Chordip Ltd. (GB) 2003-03-05 EP disclosed
US-6455718-B1 FOR CONTINUOUSLY RECOVERING CHLOROPENTAFLUOROBENZENE OR BROMOPENTAFLUOROBENZENE FROM VAPOR PHASE ALBEMARLE CORPORATION 2002-09-24 US disclosed
EP-0944564-B1 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORP (US) 2002-03-20 EP disclosed
US-6241917-B1 Halogen exchange reactions in preparing catalysts and their precursors ALBEMARLE CORPORATION 2001-06-05 US disclosed
US-6215032-B1 SOLVENT EXTRACTION; SEPARATING AMINOPHOSPHONIUM CATALYST; FLUORINATION OF HALOAROMATIC COMPOUND BY REPLACEMENT REACTION WITH ALKALI METAL FLUORIDE ALBEMARLE CORPORATION 2001-04-10 US disclosed
WO-1999040052-A1 CATALYST RECOVERY FOR HALOGEN EXCHANGE REACTIONS ALBEMARLE CORPORATION (US) 1999-08-12 WO disclosed
WO-1999026950-A1 IMPROVED CATALYSIS IN HALOGEN EXCHANGE REACTIONS ALBEMARLE CORPORATION (US) 1999-06-03 WO disclosed
US-5824827-A Halogen exchange reactions ALBEMARLE CORPORATION (US) 1998-10-20 US disclosed
US-5789631-A Production of perhalobenzenes ALBEMARLE CORPORATION (US) 1998-08-04 US disclosed
WO-1998022413-A1 HALOGEN EXCHANGE REACTIONS AND USES THEREOF ALBEMARLE CORPORATION (US) 1998-05-28 WO disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
US-5728641-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1998-03-17 US disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
US-5556821-A Catalyst component for the polymerization of olefins NIPPON OIL COMPANY, LIMITED (JP) 1996-09-17 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030163000-A1 Halogen exchange reactions and catalysts therefor WEE2, WEE1, SLC39A11 CA1 1391/4885CA2 332/4885CA4 423/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.