SCHEMBL6151918

SCHEMBL6151918

Nc1ccc2ncc3ccccc3c2c1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.64
GPR3 P46089 1/20 0.64
TLR9 Q9NR96 2/20 0.53
EGFR P00533 4/20 0.50
KMT2A Q03164 3/20 0.49
MEN1 O00255 2/20 0.49
ALDH1A1 P00352 3/20 0.48
HSD17B10 Q99714 3/20 0.48
MAPT P10636 3/20 0.48
ATM Q13315 2/20 0.48
TP53 P04637 2/20 0.48
CASP1 P29466 2/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
HSP90AA1 P07900 1/20 0.48
HSP90AB1 P08238 1/20 0.48
TSHR P16473 1/20 0.48
HTT P42858 1/20 0.48
CYP3A4 P08684 2/20 0.46
APAF1 O14727 1/20 0.45
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516897 0.85 KDM4E (0.64) KDM4EGPR3TLR9EGFRKMT2A
SCHEMBL19264891 0.85 KDM4E (0.64) KDM4EGPR3TLR9EGFRKMT2A
SCHEMBL19049164 0.83 KDM4E (0.68) KDM4EGPR3TLR9EGFRKMT2A
SCHEMBL17306545 0.83 TLR9 (0.49) KDM4EGPR3TLR9EGFRKMT2A
Hydrochloric Acid SCHEMBL6867092 0.81 KDM4E (0.66) KDM4EGPR3TLR9EGFRKMT2A
SCHEMBL2680789 0.81 KDM4E (0.71) KDM4EGPR3TLR9KMT2AMEN1
SCHEMBL19596252 0.79 KDM4E (0.62) KDM4EGPR3TLR9KMT2AMEN1
SCHEMBL28864525 0.79 KDM4E (0.62) KDM4EGPR3KMT2AMEN1MAPT
SCHEMBL840612 0.79 KDM4E (0.62) KDM4EGPR3EGFRKMT2AMEN1
SCHEMBL9020772 0.79 KDM4E (0.62) KDM4EGPR3KMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3244466-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO LTD (KR) 2021-08-04 EP disclosed
EP-3301097-B1 [1]BENZOTHIENO[3',2':4,5]IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN ORGANIC LIGHT-EMITTING DEVICES (OLEDS) SAMSUNG DISPLAY CO LTD (KR) 2020-08-19 EP disclosed
EP-3693372-A1 BENZOFURO[3',2':4,5]IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN ORGANIC LIGHT-EMITTING DEVICES (OLEDS) Samsung Display Co., Ltd. (KR) 2020-08-12 EP disclosed
CN-110256346-A Phenanthridines ketone compounds and preparation method and application with BRD4 albumen inhibiting effect 浙江省医学科学院 2019-09-20 CN disclosed
EP-3244466-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-11-15 EP disclosed
EP-3229290-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-10-11 EP disclosed
EP-1551992-A2 SCREENING MOLECULES WITH ANTI-PRION ACTIVITY: KITS, METHODS AND SCREENED MOLECULES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2005-07-13 EP disclosed
WO-2004035813-A2 SCREENING MOLECULES WITH ANTI-PRION ACTIVITY: KITS, METHODS AND SCREENED MOLECULES CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) 2004-04-29 WO disclosed