Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | RECQL | P46063 | 2/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 1.00 |
| ▸ | ABCB11 | O95342 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 1.00 |
| ▸ | ALOX15 | P16050 | 1/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | BLM | P54132 | 1/20 | 1.00 |
| ▸ | CASP7 | P55210 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
| ▸ | DDR2 | Q16832 | 1/20 | 1.00 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dactinomycin SCHEMBL3844 | 1.00 | GRB2 (1.00) | GRB2MAPTRECQLSMN1; SMN2ABCB11 | |
| Dactinomycin SCHEMBL26186613 | 1.00 | GRB2 (1.00) | GRB2MAPTRECQLSMN1; SMN2ABCB11 | |
| Dactinomycin SCHEMBL13659669 | 1.00 | GRB2 (1.00) | GRB2MAPTRECQLSMN1; SMN2ABCB11 | |
| Dactinomycin SCHEMBL27304406 | 1.00 | GRB2 (1.00) | GRB2MAPTRECQLSMN1; SMN2ABCB11 | |
| Dactinomycin SCHEMBL3845 | 1.00 | GRB2 (1.00) | GRB2MAPTRECQLSMN1; SMN2ABCB11 | |
| Dactinomycin SCHEMBL19770615 | 1.00 | GRB2 (1.00) | GRB2MAPTRECQLSMN1; SMN2ABCB11 | |
| Dactinomycin SCHEMBL6939686 | 1.00 | GRB2 (1.00) | GRB2MAPTRECQLSMN1; SMN2ABCB11 | |
| Dactinomycin SCHEMBL28168861 | 0.99 | GRB2 (0.99) | GRB2MAPTRECQLSMN1; SMN2ABCB11 | |
| Dactinomycin SCHEMBL2790145 | 0.99 | GRB2 (0.99) | GRB2MAPTRECQLSMN1; SMN2ABCB11 | |
| Dactinomycin SCHEMBL28161860 | 0.99 | GRB2 (0.98) | GRB2MAPTRECQLSMN1; SMN2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 89122 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3607938-B1 | PHARMACEUTICAL COMPOSITION | SOVIC BRKICIC LJILJANA (HR) | 2026-05-27 | — | — | EP | claimed |
| EP-4747263-A1 | LIPID NANOPARTICLES AND USES THEREOF | University of Connecticut (US) | 2026-05-27 | — | — | EP | claimed |
| CN-116209439-B | Cereblon protein modulators | Saint Jude Children's Research Hospital Ltd. (US) | 2026-05-26 | — | — | CN | claimed |
| US-20260137650-A1 | MODULATORS OF RAR RELATED ORPHAN RECEPTORS (RORs) | 11949098 CANADA INC (CA) | 2026-05-21 | — | — | US | claimed |
| WO-2026102563-A1 | DISUBSTITUTED PYRIMIDOPYRROLE ANALOG AND USE THEREOF | 深圳湾实验室坪山生物医药研发转化中心 | 2026-05-21 | — | — | WO | claimed |
| CN-122056884-A | Methods of treating pancreatic cancer | 坎莫森特里克斯公司 | 2026-05-19 | — | — | CN | claimed |
| WO-2026098621-A1 | ENGINEERED ANTIBODY WITH SITE-SPECIFIC CONJUGATION, ANTIBODY-DRUG CONJUGATE, AND APPLICATION THEREOF | 百力司康生物医药(杭州)有限公司 | 2026-05-15 | — | — | WO | claimed |
| WO-2026101236-A1 | PEPTIDES SPECIFICALLY BINDING TO CCR8, AND USE THEREOF | 경희대학교 산학협력단 | 2026-05-15 | — | — | WO | claimed |
| WO-2026102332-A1 | NERVE AND TUMOR HOMING AGENTS AND METHODS OF USE THEREOF | Blaze Bioscience, Inc. (US) | 2026-05-15 | — | — | WO | claimed |
| US-20260116861-A1 | ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS | THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) | 2026-04-30 | — | — | US | claimed |
| WO-1984001506-A1 | PHARMACEUTICAL PREPARATIONS FOR USE IN ANTITUMOUR THERAPY | UNIV BIRMINGHAM (GB) | 1984-04-26 | — | — | WO | claimed |
| US-4425737-A | USING ALPHA-AMYLASE TO IDENTIFY EMBRYO CONTAINING SEED SEGMENTS | AGRIGENETICS RESEARCH ASSOCIATES LIMITED (US) | 1984-01-17 | — | — | US | claimed |
| EP-0019167-B1 | MEDICINAL PREPARATION FOR THE TREATMENT OF CARCINOMA AND PROCESS FOR PREPARING IT | Limburg, Hans, Dr. (DE) | 1983-10-12 | — | — | EP | claimed |
| US-4401592-A | REACTION PRODUCT OF AN ANTIBODY WITH AN ANTIBIOTIC, ANTIMETABOLIC SUBSTANCE OR ALKYLATING AGENT | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1983-08-30 | — | — | US | claimed |
| US-4257774-A | Intercalation inhibition assay for compounds that interact with DNA or RNA | MELOY LABORATORIES, INC. (US) | 1981-03-24 | — | — | US | claimed |
| US-4224408-A | Deoxyribonucleic acid synthesis using binding protein | ABBOTT LABORATORIES (US) | 1980-09-23 | — | — | US | claimed |
| US-4148877-A | Fraction capable of inducing in vivo a resistance to bacterial infections, process for obtaining said fraction from bacteria and drugs containing said fraction | CHOAY S. A. (FR) | 1979-04-10 | — | — | US | claimed |
| US-4106488-A | Cancer treatment method | GORDON, DAVID, SKOKIE, ILLINOIS | 1978-08-15 | — | — | US | claimed |
| US-4078052-A | Large unilamellar vesicles (LUV) and method of preparing same | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF HEALTH, EDUCATION AND WELFARE (US) | 1978-03-07 | — | — | US | claimed |
| US-3993754-A | Liposome-encapsulated actinomycin for cancer chemotherapy | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES ENERGY RESEARCH AND DEVELOPMENT ADMINISTRATION (US) | 1976-11-23 | — | — | US | claimed |