Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.72 |
| ▸ | PPARG | P37231 | 14/20 | 0.70 |
| ▸ | PPARD | Q03181 | 8/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6152282 | 1.00 | PPARA (0.72) | PPARAPPARGPPARD | |
| SCHEMBL27674855 | 0.91 | PPARA (0.81) | PPARAPPARGPPARD | |
| SCHEMBL5802260 | 0.90 | PPARA (0.71) | PPARAPPARGPPARD | |
| SCHEMBL27654986 | 0.90 | PPARA (0.85) | PPARAPPARGPPARD | |
| SCHEMBL6151174 | 0.89 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL6149960 | 0.89 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL5801761 | 0.88 | PPARA (0.67) | PPARAPPARGPPARD | |
| SCHEMBL6388507 | 0.87 | PPARA (0.74) | PPARAPPARGPPARD | |
| SCHEMBL4758133 | 0.87 | PPARA (0.74) | PPARAPPARGPPARD | |
| SCHEMBL4755515 | 0.87 | PPARA (0.74) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |