SCHEMBL6152541

SCHEMBL6152541

Cc1noc(NS(=O)(=O)c2sccc2CCOc2ccc3c(c2)OCO3)c1Br

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EDNRB P24530 20/20 0.85
EDNRA P25101 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631498 0.92 EDNRB (1.00) EDNRBEDNRA
SCHEMBL4631574 0.85 EDNRB (1.00) EDNRBEDNRA
SCHEMBL6150959 0.84 EDNRB (0.86) EDNRBEDNRA
SCHEMBL4631487 0.83 EDNRA (1.00) EDNRBEDNRA
SCHEMBL4631842 0.82 EDNRB (1.00) EDNRBEDNRA
SCHEMBL4632010 0.80 EDNRB (1.00) EDNRBEDNRA
SCHEMBL4631412 0.80 EDNRA (0.71) EDNRBEDNRA
SCHEMBL4631418 0.78 EDNRB (1.00) EDNRBEDNRA
SCHEMBL4631448 0.77 EDNRB (0.80) EDNRBEDNRA
SCHEMBL4631444 0.77 EDNRB (0.80) EDNRBEDNRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1498419-A1 Process for preparing alkali metal salts of hydrophobic sulfonamides ENCYSIVE PHARMACEUTICALS INC. (US) 2005-01-19 EP disclosed