Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93977 | 0.89 | OR51E2 (0.50) | TDP1OR51E2 | |
| SCHEMBL2798798 | 0.88 | OR51E2 (0.40) | TDP1OR51E2TSHR | |
| Propane SCHEMBL21814344 | 0.87 | OR51E2 (0.43) | TDP1OR51E2TSHR | |
| Alcohol SCHEMBL6238241 | 0.87 | OR51E2 (0.43) | TDP1OR51E2TSHR | |
| Water SCHEMBL22418485 | 0.87 | OR51E2 (0.55) | OR51E2 | |
| SCHEMBL6249794 | 0.87 | OR51E2 (0.48) | OR51E2 | |
| SCHEMBL4985589 | 0.87 | OR51E2 (0.48) | OR51E2 | |
| Ethylene Glycol SCHEMBL3837465 | 0.84 | OR51E2 (0.46) | OR51E2 | |
| Ethylene SCHEMBL15065634 | 0.84 | OR51E2 (0.46) | OR51E2 | |
| SCHEMBL8531049 | 0.84 | OR51E2 (0.37) | TDP1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4349187-A1 | FILTER WITH ADDED LIQUID, FLAVOR INHALATION ARTICLE EQUIPPED WITH SAID FILTER, AND FLAVOR INHALATION ARTICLE PACKAGE | Japan Tobacco, Inc. (JP) | 2024-04-10 | — | — | EP | disclosed |
| US-20240074490-A1 | FILTER WITH ADDED LIQUID, FLAVOR INHALATION ARTICLE EQUIPPED WITH SAID FILTER, AND FLAVOR INHALATION ARTICLE PACKAGE | JAPAN TOBACCO INC. (JP) | 2024-03-07 | — | — | US | disclosed |
| CN-105979929-B | Composition in the form of an emulsion | 莱雅公司 | 2020-08-21 | — | — | CN | disclosed |
| CN-105722496-B | Fatty acid esters or liquid alkylpolyglucosides containing sugars with HLB <8 and C8-C18Two-phase compositions of branched alkanes | 莱雅公司 | 2020-04-28 | — | — | CN | disclosed |
| US-20150320589-A1 | HEATING TOOL | KOBAYASHI PHARMACEUTICAL CO., LTD. (JP) | 2015-11-12 | — | — | US | disclosed |
| EP-1460899-A4 | LIQUID COMPOSITIONS OF IPBC IN POLYETHYLENE GLYCOL, POLYPROPYLENE GLYCOL OR POLYPROPYLENE GLYCOL GLYCERYL ESTERS | ISP INVESTMENTS INC (US) | 2005-01-19 | — | — | EP | disclosed |
| EP-1460899-A1 | LIQUID COMPOSITIONS OF IPBC IN POLYETHYLENE GLYCOL, POLYPROPYLENE GLYCOL OR POLYPROPYLENE GLYCOL GLYCERYL ESTERS | ISP INVESTMENTS INC. (US) | 2004-09-29 | — | — | EP | disclosed |
| US-6616740-B2 | 3-iodo-2-propynyl butylcarbamate; do not contribute to the VOC of paints and coatings and is stabilized effectively against discoloration even at elevated temperatures or direct sunlight. | ISP INVESTMENTS INC. | 2003-09-09 | — | — | US | disclosed |
| WO-2003049543-A1 | LIQUID COMPOSITIONS OF IPBC IN POLYETHYLENE GLYCOL, POLYPROPYLENE GLYCOL OR POLYPROPYLENE GLYCOL GLYCERYL ESTERS | ISP INVESTMENTS INC. (US) | 2003-06-19 | — | — | WO | disclosed |
| US-20030109598-A1 | Liquid compositions of IPBC in polyethylene glycol, polypropylene glycol or polypropylene glycol glyceryl esters | ISP INVESTMENTS INC. | 2003-06-12 | — | — | US | disclosed |
| US-6110452-A | BACTERICIDES AND ANTISTICKING COATINGS FOR SUBMERGIBLE AGENTS USING POLYGLYCOL FATTY ACID ESTER OR DIESTER | BUCKMAN LABORATORIES INTERNATIONAL INC (US) | 2000-08-29 | — | — | US | disclosed |
| EP-0854842-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING POLYGLYCOL FATTY ACID ESTERS | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1998-07-29 | — | — | EP | disclosed |
| WO-1997011912-A1 | METHODS AND COMPOSITIONS FOR CONTROLLING BIOFOULING USING POLYGLYCOL FATTY ACID ESTERS | BUCKMAN LABORATORIES INTERNATIONAL, INC. (US) | 1997-04-03 | — | — | WO | disclosed |