Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9409590 | 0.86 | CA1 (0.34) | CA1CA2CA4KMT2AGABRA1 | |
| SCHEMBL6829626 | 0.86 | MEN1 (0.32) | KMT2AMEN1 | |
| SCHEMBL22862061 | 0.78 | CA1 (0.37) | CA1CA2CA4KMT2A | |
| SCHEMBL13497137 | 0.76 | MEN1 (0.35) | KMT2AMEN1 | |
| SCHEMBL15463086 | 0.74 | CA1 (0.39) | CA1CA2CA4KMT2AMEN1 | |
| SCHEMBL20969080 | 0.74 | CA1 (0.39) | CA1CA2CA4KMT2AMEN1 | |
| SCHEMBL20969085 | 0.74 | CA1 (0.39) | CA1CA2CA4KMT2AMEN1 | |
| SCHEMBL29361207 | 0.74 | — | — | |
| SCHEMBL27711787 | 0.72 | CA1 (0.42) | CA1CA2CA4KMT2AGABRA1 | |
| SCHEMBL29453962 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084109-B1 | 2-AMINOPYRIDINES CONTAINING FUSED RING SUBSTITUENTS AS NITRIC OXIDE SYNTHASE INHIBITORS | PFIZER PROD INC (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1084109-A1 | 2-AMINOPYRIDINES CONTAINING FUSED RING SUBSTITUENTS AS NITRIC OXIDE SYNTHASE INHIBITORS | Pfizer Products Inc. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062883-A1 | 2-AMINOPYRIDINES CONTAINING FUSED RING SUBSTITUENTS AS NITRIC OXIDE SYNTHASE INHIBITORS | PFIZER PRODUCTS INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| US-4031237-A | DIELS-ALDER CONDENSATION | MOBIL OIL CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |