⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL220408 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL11179226 | 0.64 | — | — | |
| SCHEMBL10701830 | 0.58 | — | — | |
| SCHEMBL7698487 | 0.58 | — | — | |
| SCHEMBL2349173 | 0.58 | — | — | |
| SCHEMBL16591163 | 0.58 | — | — | |
| SCHEMBL13780208 | 0.58 | — | — | |
| SCHEMBL8296699 | 0.58 | — | — | |
| Hydrochloric Acid SCHEMBL28924838 | 0.56 | — | — | |
| SCHEMBL11525868 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107260743-A | Azatryptamine ketone derivatives as IDO1 and/or TDO inhibitor purposes | 北京大学 | 2017-10-20 | — | — | CN | claimed |
| CN-1646125-A | Substituted pyridones as modulators of P38MAP kinase | PHARMACIA CORP (US) | 2005-07-27 | — | — | CN | claimed |
| CN-1145613-C | Cathecol hydrazone derivatives, process for preparing the same and pharmaceutical composition containing the same | ��һ������ʽ���� | 2004-04-14 | — | — | CN | claimed |
| CN-1352636-A | Cathecol hydrazone derivatives, process for preparing the same and pharmaceutical composition containing the same | CHEIL JEDANG CORP (KR) | 2002-06-05 | — | — | CN | claimed |
| CN-107501274-B | It can be used as the compound of ATR kinase inhibitor | Votex Pharmaceutical Co., Ltd. (US) | 2019-11-22 | — | — | CN | disclosed |
| CN-107501275-B | It can be used as the compound of ATR kinase inhibitor | Votex Pharmaceutical Co., Ltd. (US) | 2019-11-22 | — | — | CN | disclosed |
| CN-109963841-A | 4- ((6- (2- (2,4 difluorobenzene base) -1,1- two fluoro- 2- hydroxyl -3- (5- sulfydryl -1H-1,2,4- triazol-1-yl) propyl) pyridin-3-yl) oxygroup) benzonitrile and preparation method | 美国陶氏益农公司 | 2019-07-02 | — | — | CN | disclosed |
| CN-107311905-B | A kind of nopinone thiosemicarbazone derivative and its preparation method and application | 南京林业大学 | 2019-06-04 | — | — | CN | disclosed |
| CN-109734723-A | Ofloxacin thiazole analog and its preparation method and application | 西南大学 | 2019-05-10 | — | — | CN | disclosed |
| CN-109734640-A | Containing the thio formhydrazide derivative as I of sulfuryl, preparation method and application | 贵州大学 | 2019-05-10 | — | — | CN | disclosed |
| CN-108373536-A | A kind of synthetic method and application with schiff base structure modified polyaspartic acid | 河北工业大学 | 2018-08-07 | — | — | CN | disclosed |
| CN-108368102-A | 2- amino -1,3,4- thiadiazines and antifungal agent based on 2- amino -1,3,4- oxadiazines | F2G有限公司 | 2018-08-03 | — | — | CN | disclosed |
| US-20050065118-A1 | Organosulfur inhibitors of tyrosine phosphatases | METABASIS THERAPEUTICS, INC. | 2005-03-24 | — | — | US | disclosed |
| EP-1446110-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | Structural Bioinformatics Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| CN-1149204-C | 1-heterocyclic substituted diarylamines | ��ʲ | 2004-05-12 | — | — | CN | disclosed |
| CN-1145613-C | Cathecol hydrazone derivatives, process for preparing the same and pharmaceutical composition containing the same | ��һ������ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| WO-2003032916-A2 | ORGANOSULFUR INHIBITORS OF TYROSINE PHOSPHATASES | STRUCTURAL BIOINFORMATICS INC. (US) | 2003-04-24 | — | — | WO | disclosed |
| CN-1352636-A | Cathecol hydrazone derivatives, process for preparing the same and pharmaceutical composition containing the same | CHEIL JEDANG CORP (KR) | 2002-06-05 | — | — | CN | disclosed |
| CN-1334807-A | 1-heterocycle substd. diarylamines | WARNER LAMBERT CO (US) | 2002-02-06 | — | — | CN | disclosed |
| CN-1055180-A | 3 of thiazolinone, azoles quinoline ketone and the imidazolone type that 2-replaces, the preparation method of 5-di-tert-butyl-hydroxy phenyl methylene derivatives | WARNER LAMBERT CO (US) | 1991-10-09 | — | — | CN | disclosed |