SCHEMBL6153776

SCHEMBL6153776

C=CCOC(=O)Oc1ccccc1OC(=O)OCC=C

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.56
TSHR P16473 3/20 0.49
ALDH1A1 P00352 3/20 0.49
HSD17B10 Q99714 2/20 0.49
LIG1 P18858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.45
PKM P14618 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
KDM4E B2RXH2 2/20 0.42
RHOA P61586 1/20 0.42
MAPK1 P28482 4/20 0.41
HPGD P15428 1/20 0.41
MEN1 O00255 4/20 0.40
KMT2A Q03164 4/20 0.40
MAPT P10636 3/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
KCNA3 P22001 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6241641 0.95 CYP3A4 (0.51) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL27890950 0.92 CYP3A4 (0.49) CYP3A4TSHRALDH1A1HSD17B10SMN1; SMN2
SCHEMBL16523163 0.90 CYP3A4 (0.47) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL1598847 0.88 CYP3A4 (0.49) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL9174748 0.88 CYP3A4 (0.49) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL5605874 0.88 CYP3A4 (0.49) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL10871081 0.87 CYP3A4 (0.47) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL9717332 0.87 KDM4E (0.57) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL6240477 0.85 CYP3A4 (0.46) CYP3A4TSHRALDH1A1HSD17B10LIG1
SCHEMBL9762913 0.85 HTT (0.48) CYP3A4TSHRALDH1A1HSD17B10NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9017908-B2 Photoelectrical stable imaging members XEROX CORPORATION (US) 2015-04-28 US disclosed
US-9017908-B2 Photoelectrical stable imaging members XEROX CORPORATION (US) 2015-04-28 US disclosed
US-20150056546-A1 PHOTOELECTRICAL STABLE IMAGING MEMBERS XEROX CORPORATION (US) 2015-02-26 US disclosed
US-20150056546-A1 PHOTOELECTRICAL STABLE IMAGING MEMBERS XEROX CORPORATION (US) 2015-02-26 US disclosed
US-8263298-B1 Electrically tunable and stable imaging members XEROX CORPORATION (US) 2012-09-11 US disclosed
US-20120219893-A1 ELECTRICALLY TUNABLE AND STABLE IMAGING MEMBERS XEROX CORPORATION (US) 2012-08-30 US disclosed
US-20100297544-A1 FLEXIBLE IMAGING MEMBERS HAVING A PLASTICIZED IMAGING LAYER XEROX CORPORATION (US) 2010-11-25 US disclosed
EP-1196466-B1 POLYMERIZABLE COMPOSITION OF ALIPHATIC POLYOL (ALLYL CARBONATE) PPG IND OHIO INC (US) 2005-01-26 EP disclosed
US-6316570-B1 FOR PRODUCING POLYMERIZATES HAVING CLARITY, GOOD FLEXIBILITY, ABRASION RESISTANCE WHICH ARE USED IN PREPARATION OF MOLDED ARTICLES SUCH AS LENSES PPG INDUSTRIES OHIO, INC. 2001-11-13 US disclosed
US-5708064-A CONTAINING THERMOSETTING RESIN PPG INDUSTRIES, INC. (US) 1998-01-13 US disclosed