Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154076 | 1.00 | PTAFR (1.00) | PTAFR | |
| SCHEMBL6154080 | 1.00 | PTAFR (1.00) | PTAFR | |
| SCHEMBL7663725 | 0.92 | PTAFR (0.86) | PTAFR | |
| SCHEMBL7663727 | 0.92 | PTAFR (0.86) | PTAFR | |
| SCHEMBL7663731 | 0.92 | PTAFR (0.86) | PTAFR | |
| SCHEMBL9100931 | 0.92 | PTAFR (0.85) | PTAFR | |
| SCHEMBL9100914 | 0.92 | PTAFR (0.85) | PTAFR | |
| SCHEMBL9100923 | 0.92 | PTAFR (0.85) | PTAFR | |
| SCHEMBL7666421 | 0.91 | PTAFR (0.83) | PTAFR | |
| SCHEMBL7666431 | 0.91 | PTAFR (0.83) | PTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032713-A1 | Platelet-activating factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-10 | — | — | US | claimed |
| US-20040028756-A1 | Platelet-activated factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-12 | — | — | US | claimed |
| WO-2003082199-A2 | PLATELET-ACTIVATING FACTOR ANTAGONISTS AS ANALGESIC, ANTI-INFLAMMATORY, UTERINE CONTRACTION INHIBITING, AND ANTI-TUMOR AGENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-10-09 | — | — | WO | claimed |
| EP-0345931-B1 | CERTAIN PAF ANTAGONIST/ANTIHISTAMINE COMBINATIONS AND METHODS | SCHERING CORPORATION (US) | 1993-01-20 | — | — | EP | claimed |
| EP-0416604-A2 | PAF-antagonists for the preparation of a medicament, useful for the treatment of heart diseases, caused by diminished beta-receptor-stimulation | Dr. Karl Thomae GmbH (DE) | 1991-03-13 | — | — | EP | claimed |
| EP-0402422-A1 | CERTAIN PAF ANTAGONIST ANTIHISTAMINE COMBINATIONS AND METHODS | SCHERING CORPORATION (US) | 1990-12-19 | — | — | EP | claimed |
| EP-0345931-A1 | Certain PAF antagonist/antihistamine combinations and methods | SCHERING CORPORATION (US) | 1989-12-13 | — | — | EP | claimed |
| WO-1989010143-A1 | CERTAIN PAF ANTAGONIST ANTIHISTAMINE COMBINATIONS AND METHODS | SCHERING CORPORATION (US) | 1989-11-02 | — | — | WO | claimed |
| US-20050032713-A1 | Platelet-activating factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-02-10 | — | — | US | disclosed |
| US-20040028756-A1 | Platelet-activated factor antagonists as analgesic, anti-inflammatory, uterine contraction inhibiting, and anti-tumor agents | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2004-02-12 | — | — | US | disclosed |
| WO-2003082199-A2 | PLATELET-ACTIVATING FACTOR ANTAGONISTS AS ANALGESIC, ANTI-INFLAMMATORY, UTERINE CONTRACTION INHIBITING, AND ANTI-TUMOR AGENTS | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2003-10-09 | — | — | WO | disclosed |
| EP-0635018-B1 | 4-(1H-2-METHYLIMIDAZO[4,5-c]PYRIDINYLMETHYL)PHENYLSULPHONAMIDE DERIVATIVES AS ANTAGONISTS OF PAF | BRITISH BIO TECHNOLOGY (GB) | 1999-12-22 | — | — | EP | disclosed |
| US-5637595-A | PLATELET ACTIVATING FACTOR | BRITISH BIO-TECHNOLOGY LIMITED (GB) | 1997-06-10 | — | — | US | disclosed |
| US-5563151-A | PLATELET ACTIVATING FACTOR RECEPTOR ANTAGONISTS; ANTIINFLAMMATORY AGENTS, ANALGESICS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-10-08 | — | — | US | disclosed |
| US-5010100-A | Skeletal muscular disorders, hydertensive agents, cardiovascular disorders | MERCK & CO. INC. (US) | 1991-04-23 | — | — | US | disclosed |
| EP-0416604-A2 | PAF-antagonists for the preparation of a medicament, useful for the treatment of heart diseases, caused by diminished beta-receptor-stimulation | Dr. Karl Thomae GmbH (DE) | 1991-03-13 | — | — | EP | disclosed |
| EP-0402422-A1 | CERTAIN PAF ANTAGONIST ANTIHISTAMINE COMBINATIONS AND METHODS | SCHERING CORPORATION (US) | 1990-12-19 | — | — | EP | disclosed |
| EP-0345931-A1 | Certain PAF antagonist/antihistamine combinations and methods | SCHERING CORPORATION (US) | 1989-12-13 | — | — | EP | disclosed |
| WO-1989010143-A1 | CERTAIN PAF ANTAGONIST ANTIHISTAMINE COMBINATIONS AND METHODS | SCHERING CORPORATION (US) | 1989-11-02 | — | — | WO | disclosed |
| EP-0199324-A2 | New 2,5-diaryl tetryhydrofurans and analogs thereof as paf antagonists | MERCK & CO. INC. (US) | 1986-10-29 | — | — | EP | disclosed |