⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15099 | 1.00 | — | — | |
| SCHEMBL3276493 | 0.82 | — | — | |
| SCHEMBL1827583 | 0.73 | — | — | |
| SCHEMBL1258110 | 0.73 | — | — | |
| SCHEMBL1260052 | 0.69 | — | — | |
| SCHEMBL2085096 | 0.67 | — | — | |
| SCHEMBL1780893 | 0.67 | — | — | |
| SCHEMBL3276716 | 0.59 | — | — | |
| Morpholine SCHEMBL3664363 | 0.54 | MEN1 (0.73) | — | |
| SCHEMBL237047 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120041194-A1 | NITROGEN AND SULFUR-CONTAINING HETROCYCLE DERIVATIVES | TRIAD MULTITECH PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | US | disclosed |
| US-20110269953-A1 | Nitrogen and Sulfur-Containing Heterocycle Derivatives | ARMILLI MURTY N | 2011-11-03 | — | — | US | disclosed |
| WO-2010025436-A2 | NITROGEN AND SULFUR-CONTAINING HETEROCYCLE DERIVATIVES | TRIAD MULTITECH PHARMACEUTICALS, INC. (US) | 2010-03-04 | — | — | WO | disclosed |
| US-6869951-B1 | Method of changing conformation of a matrix metalloproteinase | PHARMACIA CORPORATION (US) | 2005-03-22 | — | — | US | disclosed |
| WO-2002003994-A1 | N SULFONYL AMINOACID DERIVATIVES AS INHIBITORS OF METALLOPROTEINASE | G.D. SEARLE & CO. (US) | 2002-01-17 | — | — | WO | disclosed |
| WO-2001005389-A2 | N-SULFONYLAMINIACID DERIVATIVES AS INHIBITORS OF METALLOPRTEINASE | G.D. SEARLE & CO. (US) | 2001-01-25 | — | — | WO | disclosed |