Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 8/20 | 0.36 |
| ▸ | PPARG | P37231 | 5/20 | 0.36 |
| ▸ | VDR | P11473 | 7/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6154202 | 1.00 | HMGCR (0.44) | HMGCRPPARAPPARGVDRKDM4E | |
| SCHEMBL6156685 | 0.99 | HMGCR (0.45) | HMGCRPPARAPPARGVDRKDM4E | |
| SCHEMBL6156678 | 0.99 | HMGCR (0.45) | HMGCRPPARAPPARGVDRKDM4E | |
| SCHEMBL6886288 | 0.92 | HMGCR (0.48) | HMGCRPPARAPPARGVDRKDM4E | |
| SCHEMBL6886291 | 0.92 | HMGCR (0.48) | HMGCRPPARAPPARGVDRKDM4E | |
| SCHEMBL6156825 | 0.85 | PPARA (0.43) | PPARAPPARGKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6156820 | 0.85 | PPARA (0.43) | PPARAPPARGKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6156193 | 0.83 | PPARA (0.41) | PPARAPPARGKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6156187 | 0.83 | PPARA (0.41) | PPARAPPARGKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6154204 | 0.83 | HMGCR (0.40) | HMGCRPPARAPPARGVDRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |