Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6038810 | 0.95 | KMT2A (0.57) | MEN1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL6038566 | 0.91 | KDM4E (0.65) | MEN1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL6038774 | 0.89 | KMT2A (0.61) | MEN1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL6038381 | 0.89 | KDM4E (0.56) | MEN1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL6038734 | 0.88 | MEN1 (0.61) | MEN1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL6038824 | 0.87 | MEN1 (0.55) | MEN1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL6038860 | 0.86 | KMT2A (0.61) | MEN1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL6038999 | 0.86 | KDM4E (0.63) | MEN1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL6038967 | 0.84 | KMT2A (0.60) | MEN1KMT2AKDM4ELMNAHSD17B10 | |
| SCHEMBL6038872 | 0.83 | KMT2A (0.60) | MEN1KMT2AKDM4ELMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1541563-A1 | CCR4 ANTAGONIST AND MEDICINAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-15 | — | — | EP | disclosed |