SCHEMBL615473

SCHEMBL615473

C=C(C)C(=O)OCC(C)C[Si](OCC)(OCC)OCC

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.53
THRB P10828 1/20 0.42
ALDH1A1 P00352 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4753687 0.92 TSHR (0.45) TSHRTHRB
SCHEMBL4751100 0.92 TSHR (0.45) TSHRTHRB
SCHEMBL2772565 0.86 TSHR (0.51) TSHRTHRBALDH1A1
SCHEMBL2772659 0.86 TSHR (0.51) TSHRTHRBALDH1A1
SCHEMBL615161 0.83 TSHR (0.56) TSHRTHRBALDH1A1
SCHEMBL16534864 0.82 TSHR (0.55) TSHRTHRBALDH1A1
SCHEMBL9301563 0.81 TSHR (0.53) TSHRTHRBALDH1A1
SCHEMBL3319370 0.78 TSHR (0.75) TSHRTHRBALDH1A1
SCHEMBL2334126 0.78 TSHR (0.58) TSHRTHRBALDH1A1
SCHEMBL4751405 0.78 TSHR (0.46) TSHRTHRBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4263868-A1 NANOARRAYS AND METHODS OF USE THEREOF Singular Genomics Systems, Inc. (US) 2023-10-25 EP claimed
WO-2022192671-A1 NANOARRAYS AND METHODS OF USE THEREOF Singular Genomics Systems, Inc. (US) 2022-09-15 WO claimed
EP-2421874-B1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2015-09-30 EP claimed
US-8979996-B2 Composition containing quaternary amino-functional organosilicon compunds and production and use thereof EVONIK DEGUSSA GMBH (DE) 2015-03-17 US claimed
EP-1799750-B1 POLYETHER-FUNCTIONAL SILOXANES, POLYETHER SILOXANE-CONTAINING COMPOSITIONS, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2014-09-17 EP claimed
US-20140208981-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF EVONIK DEGUSSA GMBH (DE) 2014-07-31 US claimed
US-8728225-B2 Composition containing quaternary amino-functional organosilicon compounds and production and use thereof EVONIK DEGUSSA GMBH (DE) 2014-05-20 US claimed
US-8236918-B2 Polyether-functional siloxanes, polyether siloxane-containing compositions, methods for the production thereof and use thereof EVONIK DEGUSSA GMBH (DE) 2012-08-07 US claimed
CN-102516776-A Polyether-functional siloxanes, polyether siloxane-containing compositions, methods for the production thereof and use thereof DEGUSSA 2012-06-27 CN claimed
EP-2421874-A1 COMPOSITION CONTAINING QUATERNARY AMINO-FUNCTIONAL ORGANOSILICON COMPOUNDS AND PRODUCTION AND USE THEREOF Evonik Degussa GmbH (DE) 2012-02-29 EP claimed
EP-1245627-B1 Organic silicon nano-microhybrid system or micro-hybrid system containing compositions for scratch and abrasion resistant coatings DEGUSSA (DE) 2007-07-04 EP claimed
EP-1799750-A1 POLYETHER-FUNCTIONAL SILOXANES, POLYETHER SILOXANE-CONTAINING COMPOSITIONS, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF Degussa GmbH (DE) 2007-06-27 EP claimed
WO-2006037380-A1 POLYETHER-FUNCTIONAL SILOXANES, POLYETHER SILOXANE-CONTAINING COMPOSITIONS, METHODS FOR THE PRODUCTION THEREOF AND USE THEREOF DEGUSSA GMBH (DE) 2006-04-13 WO claimed
US-20060063002-A1 Polymerizable organosilicon nanocapsules DEGUSSA AG (DE) 2006-03-23 US claimed
US-6699586-B2 Organosilicon nano/microhybrid or microhybrid system composition for scratch and abrasion resistant coatings DEGUSSA AG (DE) 2004-03-02 US claimed
US-20020197475-A1 Organosilicon nano/microhybrid or microhybrid system composition for scratch and abrasion resistant coatings DEGUSSA AG (DE) 2002-12-26 US claimed
EP-1249470-A2 Highly filled pasty siliconorganic nano and/or microhybridcapsules containing composition for scratch and/or abrasion resistant coatings Degussa AG (DE) 2002-10-16 EP claimed
EP-1245627-A2 Organic silicon nano-microhybrid system or micro-hybrid system containing compositions for scratch and abrasion resistant coatings Degussa AG (DE) 2002-10-02 EP claimed
US-20020098243-A1 For use in scratch resistant coatings for automobiles; comprises organosilicon compound/polymer shell and metal oxide core which are covalently attached DEGUSSA AG (DE) 2002-07-25 US claimed
EP-1195416-A2 Polymerisable silicone-organic nanocapsules Degussa AG (DE) 2002-04-10 EP claimed