Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.37 |
| ▸ | TUBB | P07437 | 2/20 | 0.37 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.37 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.37 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.37 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.37 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.37 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.37 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.37 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.37 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.37 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.37 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.37 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6156088 | 0.94 | CYP19A1 (0.36) | CYP19A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6156398 | 0.84 | CYP19A1 (0.36) | CYP19A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6154788 | 0.84 | TUBB1 (0.39) | CYP19A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6155536 | 0.83 | CYP19A1 (0.35) | CYP19A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6155189 | 0.83 | TUBB1 (0.39) | CYP19A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6154960 | 0.83 | CHRM2 (0.40) | CYP19A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6155581 | 0.82 | KDM4E (0.42) | CYP19A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6887229 | 0.81 | KDM4E (0.39) | CYP19A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6155410 | 0.81 | CHRM2 (0.39) | CYP19A1TUBB1TUBB4ATUBBTUBA3C | |
| SCHEMBL6156413 | 0.80 | KDM4E (0.38) | CYP19A1TUBB1TUBB4ATUBBTUBA3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |