⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10906223 | 0.89 | CYP2D6 (0.32) | — | |
| SCHEMBL27534335 | 0.78 | — | — | |
| SCHEMBL19812525 | 0.75 | — | — | |
| SCHEMBL22490939 | 0.75 | — | — | |
| SCHEMBL8422535 | 0.75 | — | — | |
| SCHEMBL277362 | 0.73 | — | — | |
| SCHEMBL9003812 | 0.73 | — | — | |
| SCHEMBL15314520 | 0.73 | — | — | |
| SCHEMBL5170124 | 0.73 | — | — | |
| SCHEMBL19250273 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2200687-A | — | — | None | — | — | JP | disclosed |
| CN-119317482-A | Delivery particles based on amine-thiol-ene conjugates and derivatives | 恩盖普有限公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-118660725-A | Biological valve material and preparation method and application thereof | 四川大学 | 2024-09-17 | — | — | CN | disclosed |
| CN-107406422-B | Pyrazole derivatives as sGC stimulators | 赛科理音医疗有限公司 | 2022-02-01 | — | — | CN | disclosed |
| EP-3194382-B1 | PYRAZOLE DERIVATIVES AS SGC STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2021-09-08 | — | — | EP | disclosed |
| US-20210221793-A1 | PYRAZOLE DERIVATIVES AS SGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2021-07-22 | — | — | US | disclosed |
| EP-3230276-B1 | GLP-1 RECEPTOR MODULATORS | CELGENE INT II SARL (CH) | 2020-09-02 | — | — | EP | disclosed |
| CN-111163761-A | Targeted drugs related to trimethylamine and/or trimethylamine-N-oxide | 普梭梅根公司 | 2020-05-15 | — | — | CN | disclosed |
| US-20190284168-A1 | PYRAZOLE DERIVATIES AS SGC STIMULATORS | IRONWOOD PHARMACEUTICALS, INC | 2019-09-19 | — | — | US | disclosed |
| US-20190031641-A1 | PYRAZOLE DERIVATIVES AS SGC STIMULATORS | CYCLERION THERAPEUTICS, INC. | 2019-01-31 | — | — | US | disclosed |
| US-20030144521-A1 | Process for the preparation of nonracemic syn-1-(4-hydroxy-phenyl)-2-(4-hydroxy-4-phenyl -piperidin-1-yl)-1-propanol compounds | DSM CATALYTICA PHARMACEUTICALS, INC. | 2003-07-31 | — | — | US | disclosed |
| CN-1070199-C | Oligomeric sterically hindered polyamide crosslinkers and coating compositions containing the same | AKZO NOBEL NV (NL) | 2001-08-29 | — | — | CN | disclosed |
| US-5712363-A | REDUCED VOC, AUTOMOTIVE FINISHES, REACTIVE WITH ACRYLIC POLYMER | AKZO NOBEL NV (NL) | 1998-01-27 | — | — | US | disclosed |
| EP-0678105-B1 | OLIGOMERIC STERICALLY HINDERED POLYAMIDE CROSSLINKERS AND COATING COMPOSITIONS CONTAINING THE SAME | AKZO NOBEL NV (NL) | 1997-12-03 | — | — | EP | disclosed |
| CN-1115985-A | Oligomeric sterically hindered polyamide crosslinkers and coating compositions containing the same | AKZO NV (NL) | 1996-01-31 | — | — | CN | disclosed |
| EP-0678105-A1 | OLIGOMERIC STERICALLY HINDERED POLYAMIDE CROSSLINKERS AND COATING COMPOSITIONS CONTAINING THE SAME | Akzo Nobel N.V. (NL) | 1995-10-25 | — | — | EP | disclosed |
| WO-1994015974-A1 | OLIGOMERIC STERICALLY HINDERED POLYAMIDE CROSSLINKERS AND COATING COMPOSITIONS CONTAINING THE SAME | AKZO N.V. (NL) | 1994-07-21 | — | — | WO | disclosed |
| JP-H02200687-A | THIAZOLE COMPOUND, ITS PRODUCTION AND HERBICIDE CONTAINING THE COMPOUND AS ACTIVE COMPONENT | MITSUI TOATSU CHEM INC | 1990-08-08 | — | — | JP | disclosed |
| US-4726835-A | Herbicidal and plant growth regulating imidazoline derivatives | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1988-02-23 | — | — | US | disclosed |
| EP-0227967-A2 | Imidazoline derivatives, process for preparing same, herbicide containing same, and plant growth regulator containing same | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1987-07-08 | — | — | EP | disclosed |