SCHEMBL6155435

SCHEMBL6155435

C/C(=C/O)Cc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 2/20 0.46
CES2 O00748 1/20 0.46
AKR1B1 P15121 1/20 0.46
ALDH1A1 P00352 4/20 0.40
TSHR P16473 3/20 0.40
TP53 P04637 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
TRPA1 O75762 1/20 0.40
CYP3A4 P08684 1/20 0.39
CYP2C9 P11712 1/20 0.39
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
NOS2 P35228 1/20 0.39
MAOB P27338 1/20 0.39
CYP2D6 P10635 1/20 0.38
CYP2C19 P33261 1/20 0.38
MAPK1 P28482 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3937723 1.00 CES1 (0.46) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL28581850 0.84 CYP3A4 (0.45) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL523309 0.83 CES1 (0.48) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL140663 0.79 CES1 (0.44) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL1586708 0.79 CES1 (0.44) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL11034643 0.79 CES1 (0.44) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL95525 0.79 CES1 (0.50) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL11034645 0.79 CES1 (0.44) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL95524 0.79 CES1 (0.50) CES1CES2AKR1B1ALDH1A1TSHR
SCHEMBL11074864 0.77 CES1 (0.43) CES1CES2AKR1B1ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1200546-B1 ESTERS AND DIESTERS OF 3-CYCLOHEXYL-2-METHYL-1-PROPANOL, PERFUMED ARTICLES CONTAINING THEM AND METHOD OF IMPARTING FRAGRANCE BUSH BOAKE ALLEN INC (US) 2005-02-02 EP disclosed
EP-1200546-A4 FRAGRANCE MATERIALS BUSH BOAKE ALLEN INC (US) 2003-07-16 EP disclosed
EP-1200546-A1 FRAGRANCE MATERIALS Bush Boake Allen Inc. (US) 2002-05-02 EP disclosed
US-6187727-B1 USE OF 2-METHYL-3-CYCLOHEXYLPROPANOL, ESTERS THEREOF OR MIXTURES THEREOF BUSH BOAKE ALLEN, INC. 2001-02-13 US disclosed
WO-2001004253-A1 FRAGRANCE MATERIALS BUSH BOAKE ALLEN INC. (US) 2001-01-18 WO disclosed