Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 20/20 | 0.48 |
| ▸ | PPARG | P37231 | 15/20 | 0.48 |
| ▸ | PPARD | Q03181 | 10/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353590 | 0.88 | PPARA (0.48) | PPARAPPARGPPARD | |
| SCHEMBL6156186 | 0.87 | PPARA (0.50) | PPARAPPARGPPARD | |
| SCHEMBL6677438 | 0.87 | PPARA (0.50) | PPARAPPARGPPARD | |
| SCHEMBL5363045 | 0.83 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL5358896 | 0.83 | PPARA (0.60) | PPARAPPARGPPARD | |
| SCHEMBL6158972 | 0.82 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL5358915 | 0.81 | PPARA (0.53) | PPARAPPARGPPARD | |
| SCHEMBL5365647 | 0.81 | PPARA (0.48) | PPARAPPARGPPARD | |
| SCHEMBL5354573 | 0.81 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL6151966 | 0.80 | PPARA (0.48) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | claimed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | claimed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | claimed |
| EP-1517882-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-30 | — | — | EP | disclosed |
| WO-2004000789-A9 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2004-03-11 | — | — | WO | disclosed |
| WO-2004000789-A1 | AMIDE LINKER PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | ELI LILLY AND COMPANY (US) | 2003-12-31 | — | — | WO | disclosed |