SCHEMBL6155686

SCHEMBL6155686

CCOC(=O)[C@H](Cc1ccc(-c2cccc(NC)c2)cc1)Nc1ccccc1C(=O)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 20/20 0.52
PPARA Q07869 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6155687 1.00 PPARG (0.52) PPARGPPARA
SCHEMBL2851680 0.89 PPARG (0.63) PPARG
SCHEMBL2851685 0.89 PPARG (0.63) PPARG
SCHEMBL6156263 0.84 PPARG (0.48) PPARGPPARA
SCHEMBL2853890 0.84 PPARG (0.48) PPARGPPARA
SCHEMBL4159916 0.84 PPARG (0.61) PPARGPPARA
SCHEMBL2851883 0.81 PPARG (0.51) PPARGPPARA
SCHEMBL2847839 0.79 PPARG (0.47) PPARGPPARA
SCHEMBL3439078 0.77 TP53 (0.41) PPARG
SCHEMBL3439077 0.77 HSD17B2 (0.46) PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1575911-A2 BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS Galderma Research & Development, S.N.C. (FR) 2005-09-21 EP disclosed
WO-2004046091-A2 BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) 2004-06-03 WO disclosed