Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 19/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6673569 | 0.82 | PDE10A (0.32) | PDE10A | |
| SCHEMBL6674429 | 0.82 | PDE10A (0.33) | PDE10A | |
| SCHEMBL1388163 | 0.80 | PDE10A (0.35) | PDE10A | |
| SCHEMBL5964670 | 0.79 | PDE10A (0.46) | PDE10A | |
| SCHEMBL6155336 | 0.78 | MAP4K1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7326791 | 0.78 | PDE10A (0.45) | PDE10A | |
| SCHEMBL1387994 | 0.77 | PDE10A (0.48) | PDE10A | |
| SCHEMBL1387905 | 0.76 | CHRM3 (0.48) | PDE10A | |
| Hydrochloric Acid SCHEMBL7032743 | 0.76 | PDE10A (0.47) | PDE10A | |
| Hydrochloric Acid SCHEMBL7027686 | 0.75 | CHRM3 (0.47) | PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0912575-B1 | PROCESSES FOR THE SYNTHESIS OF CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITORY ACTIVITY | EURO CELTIQUE SA (LU) | 2005-02-02 | — | — | EP | disclosed |
| US-6310205-B1 | Hypoxathine compounds | EURO-CELTIQUE, S.A. (LU) | 2001-10-30 | — | — | US | disclosed |
| EP-0912575-A4 | IMPROVED METHODS FOR THE SYNTHESIS OF CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITORY ACTIVITY | EURO CELTIQUE SA (LU) | 2001-04-25 | — | — | EP | disclosed |
| EP-0912575-A1 | IMPROVED METHODS FOR THE SYNTHESIS OF CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITORY ACTIVITY | Euro-Celtique S.A. (LU) | 1999-05-06 | — | — | EP | disclosed |
| US-5864037-A | Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity | EURO-CELTIQUE, S.A. (LU) | 1999-01-26 | — | — | US | disclosed |
| WO-1997046561-A1 | IMPROVED METHODS FOR THE SYNTHESIS OF CHEMICAL COMPOUNDS HAVING PDE-IV INHIBITORY ACTIVITY | EURO-CELTIQUE, S.A. (LU) | 1997-12-11 | — | — | WO | disclosed |