Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | DUT | P33316 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9469042 | 0.87 | BACE1 (0.34) | IDO1BACE1PREP | |
| SCHEMBL31537474 | 0.85 | IDO1 (0.36) | IDO1BACE1 | |
| SCHEMBL6119427 | 0.85 | BACE1 (0.33) | IDO1BACE1PREP | |
| SCHEMBL12002597 | 0.85 | IDO1 (0.57) | IDO1BACE1 | |
| SCHEMBL1367295 | 0.85 | IDO1 (0.38) | IDO1BACE1 | |
| SCHEMBL4513196 | 0.79 | GAA (0.37) | BACE1PREP | |
| SCHEMBL3366390 | 0.79 | IDO1 (0.38) | IDO1BACE1 | |
| SCHEMBL6885043 | 0.79 | BACE1 (0.33) | BACE1 | |
| SCHEMBL17798345 | 0.79 | BACE1 (0.36) | IDO1BACE1 | |
| SCHEMBL6438766 | 0.77 | IDO1 (0.53) | IDO1BACE1DUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |