Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | CA5A | P35218 | 2/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10455271 | 0.81 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2CA4 | |
| SCHEMBL29980026 | 0.75 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2CA4 | |
| SCHEMBL7113981 | 0.75 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2CA4 | |
| SCHEMBL8719331 | 0.75 | CYP3A4 (0.45) | TDP1CYP3A4ESR1ESR2CA4 | |
| SCHEMBL4821057 | 0.75 | CYP3A4 (0.45) | TDP1CYP3A4ESR1ESR2CA4 | |
| SCHEMBL1518031 | 0.75 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2CA4 | |
| SCHEMBL7532752 | 0.75 | CYP3A4 (0.45) | TDP1CYP3A4ESR1ESR2CA4 | |
| SCHEMBL8721614 | 0.75 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2CA4 | |
| SCHEMBL4973930 | 0.75 | TDP1 (0.45) | TDP1CYP3A4ESR1ESR2CA4 | |
| SCHEMBL3155593 | 0.75 | CYP3A4 (0.45) | TDP1CYP3A4ESR1ESR2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1525631-A2 | REDUCTION OF THE CONTACT RESISTANCE IN ORGANIC FIELD EFFECT TRANSISTORS COMPRISING PALLADIUM CONTACTS BY THE USE OF PHOSPHINES AND PHOSPHINES CONTAINING METAL | Infineon Technologies AG (DE) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004017440-A2 | REDUCTION OF THE CONTACT RESISTANCE IN ORGANIC FIELD EFFECT TRANSISTORS COMPRISING PALLADIUM CONTACTS BY THE USE OF PHOSPHINES AND PHOSPHINES CONTAINING METAL | INFINEON TECHNOLOGIES AG (DE) | 2004-02-26 | — | — | WO | disclosed |