Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CES2 | O00748 | 4/20 | 0.36 |
| ▸ | CES1 | P23141 | 4/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.33 |
| ▸ | LSS | P48449 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25549720 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL25701968 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL2144778 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| Hydrochloric Acid SCHEMBL6878837 | 0.97 | TSHR (0.41) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL25701958 | 0.97 | TSHR (0.50) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL14776804 | 0.97 | TSHR (0.47) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL10418032 | 0.93 | TSHR (0.53) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL2144618 | 0.93 | TSHR (0.53) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL11136138 | 0.93 | TSHR (0.53) | TSHRTHRBLMNACES2CES1 | |
| SCHEMBL9062821 | 0.93 | TSHR (0.53) | TSHRTHRBLMNACES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1948283-A | Process for preparing vitamin D derivatives | TAIYAO CHEMICAL CO LTD (CN) | 2007-04-18 | — | — | CN | claimed |
| CN-115346921-A | Semiconductor structure | 台湾积体电路制造股份有限公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-106662782-B | Liquid crystal sealing agent and the liquid crystal display for using it | 日本化药株式会社 | 2019-07-26 | — | — | CN | disclosed |
| CN-107759591-A | GRAPIPRANT crystal form | 阿莱塔纳治疗学股份有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107759590-A | GRAPIPRANT crystal form | 阿莱塔纳治疗学股份有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107759589-A | GRAPIPRANT crystal form | 阿莱塔纳治疗学股份有限公司 | 2018-03-06 | — | — | CN | disclosed |
| CN-107573339-A | GRAPIPRANT crystal form | 阿莱塔纳治疗学股份有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-107540671-A | GRAPIPRANT crystal form | 阿莱塔纳治疗学股份有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107501262-A | GRAPIPRANT crystal form | 阿莱塔纳治疗学股份有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-107501263-A | GRAPIPRANT crystal form | 阿莱塔纳治疗学股份有限公司 | 2017-12-22 | — | — | CN | disclosed |
| CN-101395135-A | Novel primary amides | ACTELION PHARMACEUTICALS LTD (CH) | 2009-03-25 | — | — | CN | disclosed |
| CN-101184733-A | Novel piperidine carboxylic acid amide derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2008-05-21 | — | — | CN | disclosed |
| CN-1948283-A | Process for preparing vitamin D derivatives | TAIYAO CHEMICAL CO LTD (CN) | 2007-04-18 | — | — | CN | disclosed |
| CN-1282636-C | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2006-11-01 | — | — | CN | disclosed |
| EP-1124779-B1 | VITAMIN D ANALOGUES | GALDERMA RES & DEV (FR) | 2005-02-02 | — | — | EP | disclosed |
| CN-1391235-A | Porous material | HEPLY CORP (US) | 2003-01-15 | — | — | CN | disclosed |
| CN-1332711-A | Vitamin D analogues | GALDERMA RES & DEV (FR) | 2002-01-23 | — | — | CN | disclosed |
| EP-1124779-A1 | VITAMIN D ANALOGUES | Galderma Research & Development, S.N.C. (FR) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026167-A1 | VITAMIN D ANALOGUES | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2000-05-11 | — | — | WO | disclosed |
| CN-85109061-A | The preparation method of novel acid benzazolyl compounds | — | 1987-01-21 | — | — | CN | disclosed |