SCHEMBL615687

SCHEMBL615687

N#CNC(=O)CCCCC(=O)NC#N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 3/20 0.43
HDAC2 Q92769 3/20 0.43
HDAC3 O15379 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
HDAC6 Q9UBN7 2/20 0.43
HDAC5 Q9UQL6 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.36
TSHR P16473 1/20 0.36
HSP90AA1 P07900 1/20 0.36
FAAH O00519 2/20 0.34
KDM4E B2RXH2 1/20 0.34
RECQL P46063 1/20 0.34
HDAC4 P56524 1/20 0.33
HDAC7 Q8WUI4 1/20 0.33
HDAC10 Q969S8 1/20 0.33
HDAC11 Q96DB2 1/20 0.33
HDAC9 Q9UKV0 1/20 0.33
MCL1 Q07820 1/20 0.33
MMP3 P08254 1/20 0.33
ALDH1A1 P00352 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10634612 0.97 HDAC1 (0.48) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL10631623 0.94 KDM4E (0.39) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL10500311 0.91 HDAC3 (0.37) HDAC1HDAC2HDAC3HDAC8HDAC6
SCHEMBL3295884 0.89 HSP90AA1 (0.54) SMN1; SMN2TSHRHSP90AA1FAAHHDAC11
SCHEMBL10631952 0.88 MCL1 (0.36) KDM4EMCL1
Palmitoyalcyanamide SCHEMBL3296666 0.87 HSP90AA1 (0.57) TSHRHSP90AA1FAAHHDAC11ALDH1A1
SCHEMBL3294110 0.87 HSP90AA1 (0.57) TSHRHSP90AA1FAAHHDAC11ALDH1A1
SCHEMBL3295680 0.87 HSP90AA1 (0.57) TSHRHSP90AA1FAAHHDAC11ALDH1A1
SCHEMBL3297352 0.87 HSP90AA1 (0.57) TSHRHSP90AA1FAAHHDAC11ALDH1A1
Stearoylcyanamide SCHEMBL3297220 0.87 HSP90AA1 (0.57) TSHRHSP90AA1FAAHHDAC11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834574-B2 Dual cure additive manufacturing resins for production of flame retardant objects CARBON, INC. (US) 2023-12-05 US disclosed
US-11833744-B2 Dual precursor resin systems for additive manufacturing with dual cure resins CARBON, INC. (US) 2023-12-05 US disclosed
US-11814472-B2 Epoxy dual cure resins for additive manufacturing CARBON, INC. (US) 2023-11-14 US disclosed
US-20230143277-A1 DUAL CURE STEREOLITHOGRAPHY RESINS CONTAINING DIELS-ALDER ADDUCTS CARBON INC (US) 2023-05-11 US disclosed
US-11629202-B2 Dual cure stereolithography resins containing thermoplastic particles CARBON, INC. (US) 2023-04-18 US disclosed
EP-3849806-B1 DUAL CURE ADDITIVE MANUFACTURING RESINS FOR PRODUCTION OF FLAME RETARDANT OBJECTS CARBON INC (US) 2023-04-05 EP disclosed
US-20230095097-A1 TOUGH, HIGH TEMPERATURE POLYMERS PRODUCED BY STEREOLITHOGRAPHY CARBON INC (US) 2023-03-30 US disclosed
US-11555095-B2 Dual cure resin for the production of moisture-resistant articles by additive manufacturing CARBON, INC. (US) 2023-01-17 US disclosed
US-11535686-B2 Tough, high temperature polymers produced by stereolithography CARBON, INC. (US) 2022-12-27 US disclosed
US-20220325093-A1 DUAL CURE ADDITIVE MANUFACTURING RESINS FOR PRODUCTION OF FLAME RETARDANT OBJECTS CARBON INC (US) 2022-10-13 US disclosed
EP-1414902-B1 EPOXY RESIN HUNTSMAN ADV MAT SWITZERLAND (CH) 2007-02-28 EP disclosed
US-20040234773-A1 A curable liquid blends comprising amines, latent curing agent which does not react until temperatures above 70 degrees C., a photopolymerizable compound and a photoinitiator; use as impregnating resins, forming fibre-reinforced composite materials HUNTSMAN ADVANCED MATERIALS AMERICAS INC. (N/K/A HUNTSMAN ADVANCED MATERIALS AMERICAS LLC) 2004-11-25 US disclosed
EP-1414902-A1 EPOXY RESIN Vantico AG (CH) 2004-05-06 EP disclosed
WO-2003011971-A1 EPOXY RESIN VANTICO AG (CH) 2003-02-13 WO disclosed
EP-1185574-A2 POLY(MERCAPTOPROPYLARYL) CURATIVES Lord Corporation (US) 2002-03-13 EP disclosed
US-6313257-B1 Poly (mercaptopropylaryl) curatives LORD CORPORATION 2001-11-06 US disclosed
WO-2001000698-A2 POLY(MERCAPTOPROPYLARYL) CURATIVES LORD CORPORATION (US) 2001-01-04 WO disclosed
US-5214098-A Dicyandiamide, impregnation of fiber composites, prepregs CIBA-GEIGY CORPORATION (US) 1993-05-25 US disclosed
US-4721770-A MOLDING MATERIALS CIBA-GEIGY CORPORATION (US) 1988-01-26 US disclosed
US-4618712-A HARDENER FOR EPOXIDE RESINS CIBA-GEIGY CORPORATION (US) 1986-10-21 US disclosed