Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | HPN | P05981 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2849746 | 1.00 | PPARG (0.36) | PPARGPTPN1PPARAHPNST14 | |
| SCHEMBL2851730 | 0.90 | PPARG (0.41) | PPARGPPARAHPNST14 | |
| SCHEMBL2851732 | 0.90 | PPARG (0.41) | PPARGPPARAHPNST14 | |
| SCHEMBL2859244 | 0.87 | PPARG (0.40) | PPARGPPARAHPNST14 | |
| SCHEMBL2859247 | 0.87 | PPARG (0.40) | PPARGPPARAHPNST14 | |
| SCHEMBL2849743 | 0.86 | PPARG (0.46) | PPARGPTPN1 | |
| SCHEMBL2854526 | 0.86 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL2854528 | 0.86 | PPARG (0.40) | PPARGPPARA | |
| SCHEMBL2851721 | 0.85 | PPARG (0.39) | PPARGPPARA | |
| SCHEMBL2851713 | 0.85 | PPARG (0.39) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004046091-A2 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMA TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2004-06-03 | — | — | WO | disclosed |