Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | TACR3 | P29371 | 2/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4624847 | 0.81 | ITGB1 (0.55) | ITGB1ITGAVABL1ITGA4ITGB7 | |
| SCHEMBL3314709 | 0.79 | ITGB1 (0.63) | ITGB1ITGAVABL1ITGA4ITGB7 | |
| SCHEMBL3312626 | 0.79 | ITGB1 (0.53) | ITGB1ITGAVABL1ITGA4ITGB7 | |
| SCHEMBL3321001 | 0.78 | ITGB1 (0.60) | ITGB1ITGAVABL1ITGA4ITGB7 | |
| SCHEMBL6146195 | 0.78 | ITGB1 (0.54) | ITGB1ITGAVABL1ITGA4ITGB7 | |
| SCHEMBL5127858 | 0.78 | ITGB1 (0.71) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3313415 | 0.77 | ITGB1 (0.59) | ITGB1ITGAVABL1ITGA4ITGB7 | |
| SCHEMBL4750010 | 0.77 | ITGB1 (0.59) | ITGB1ITGAVABL1ITGA4ITGB7 | |
| SCHEMBL13398404 | 0.77 | ITGB1 (0.64) | ITGB1ITGAVABL1ITGA4ITGB7 | |
| SCHEMBL3316824 | 0.74 | ITGB1 (0.56) | ITGB1ITGAVABL1ITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406932-A4 | QUICK CURING COMPOSITION | KANEKA CORP (JP) | 2005-03-23 | — | — | EP | disclosed |
| EP-1501801-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | UCB, S.A. (BE) | 2005-02-02 | — | — | EP | disclosed |
| EP-1406932-A1 | QUICK CURING COMPOSITION | KANEKA CORPORATION (JP) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003093237-A1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES, PROCESSES FOR PREPARING THEM AND THEIR USES AS VLA-4 INHIBITORS | UCB, S.A. (BE) | 2003-11-13 | — | — | WO | disclosed |
| WO-2003000749-A1 | QUICK CURING COMPOSITION | KANEKA CORPORATION (JP) | 2003-01-03 | — | — | WO | disclosed |